CRUN

Publications

" Our main objective is to develop and maintain over time a good expertise and infrastructure ensuring high quality training and clinical research."
Prof Halidou TINTO, PharmD, Msc, PhD Head of the CRUN

197 entries « 2 of 10 »

2021

Paul Sondo; Marc Christian Tahita; Toussaint Rouamba; Karim Derra; Bérenger Kaboré; Cheick Sa"id Compaoré; Florence Ouédraogo; Eli Rouamba; Hamidou Ilboudo; Estelle A"issa Bambara; Macaire Nana; Edmond Yabré Sawadogo; Hermann Sorgho; Athanase Mwinessobaonfou Somé; Innocent Valéa; Prabin Dahal; Maminata Traoré/Coulibaly; Halidou Tinto

Assessment of a combined strategy of seasonal malaria chemoprevention and supplementation with vitamin A, zinc and Plumpy’Doz™ to prevent malaria and malnutrition in children under 5 years old in Burkina Faso: a randomized open-label trial (SMC-NUT) (Journal Article)

In: Trials, 22 (1), pp. 360, 2021, ISSN: 1745-6215, (PMID: 34030705 PMCID: PMC8142067).

(Abstract | Links | BibTeX | Altmetric | Tags: Antimalarials/adverse effects, Burkina Faso/epidemiology, Chemoprevention, Child, Child Nutrition Disorders, Dietary Supplements, Humans, Infant, Malaria, Malaria/diagnosis/epidemiology/prevention & control, Malnutrition, Malnutrition/diagnosis/drug therapy/prevention & control, Pharmaceutical Preparations, Plumpy’Doz™, Preschool, Randomized controlled trial, Seasonal chemoprevention, Seasons, Vitamin A, Vitamin A/adverse effects, Zinc)

Assessment of a combined strategy of seasonal malaria  chemoprevention and supplementation with vitamin A, zinc and  Plumpy'Doz™ to prevent malaria and malnutrition in children  under 5 years old in Burkina Faso: a randomized open-label trial  (SMC-NUT)

Joel D Bognini; Sekou Samadoulougou; Mady Ouedraogo; Tiga David Kangoye; Carine Van Malderen; Halidou Tinto; Fati Kirakoya-Samadoulougou

Socioeconomic inequalities in curative healthcare-seeking for children under five before and after the free healthcare initiative in Sierra Leone: analysis of population-based survey data (Journal Article)

In: Int. J. Equity Health, 20 (1), pp. 124, 2021, ISSN: 1475-9276, (PMID: 34020665 PMCID: PMC8140517).

(Abstract | Links | BibTeX | Altmetric | Tags: Adolescent, Adult, Child, Children under five, Delivery of Health Care/economics, Female, Health Care Surveys, Healthcare Disparities/economics/statistics & numerical data, Healthcare utilization, Humans, Infant, Male, Parents/psychology, Patient Acceptance of Health Care/statistics & numerical data, Preschool, Sierra Leone, Socioeconomic Factors, Young Adult)

Socioeconomic inequalities in curative healthcare-seeking for  children under five before and after the free healthcare  initiative in Sierra Leone: analysis of population-based survey  data

Yeka Adoke; Rella Zoleko-Manego; Serge Ouoba; Alfred B Tiono; Grace Kaguthi; Juv^encio Eduardo Bonzela; Tran Thanh Duong; Alain Nahum; Marielle Bouyou-Akotet; Bernhards Ogutu; Alphonse Ouedraogo; Fiona Macintyre; Andreas Jessel; Bart Laurijssens; Mohammed H Cherkaoui-Rbati; Cathy Cantalloube; Anne Claire Marrast; Rapha"el Bejuit; David White; Timothy N C Wells; Florian Wartha; Didier Leroy; Afizi Kibuuka; Ghyslain Mombo-Ngoma; Daouda Ouattara; Ir`ene Mugenya; Bui Quang Phuc; Francis Bohissou; Denise P Mawili-Mboumba; Fredrick Olewe; Issiaka Soulama; Halidou Tinto; FALCI Study Group

A randomized, double-blind, phase 2b study to investigate the efficacy, safety, tolerability and pharmacokinetics of a single-dose regimen of ferroquine with artefenomel in adults and children with uncomplicated Plasmodium falciparum malaria (Journal Article)

In: Malar. J., 20 (1), pp. 222, 2021, ISSN: 1475-2875, (PMID: 34011358 PMCID: PMC8135182).

(Abstract | Links | BibTeX | Altmetric | Tags: Adamantane/administration & dosage/analogs & derivatives, Adolescent, Adult, Aged, Aminoquinolines/administration & dosage, Benin, Burkina Faso, C580Y, Child, Combination treatment, Double-Blind Method, Drug Combinations, Exposure–response, Falciparum/prevention & control, Female, Ferroquine, Ferrous Compounds/administration & dosage, Gabon, Humans, Infant, Kelch-13 mutation, Kenya, Malaria, Male, Metallocenes/administration & dosage, Middle Aged, Mozambique, Parasite clearance, Peroxides/administration & dosage, Pharmacokinetics/pharmacodynamics, Plasmodium falciparum/drug effects, Preschool, resistance, Uganda, Vietnam, Vomiting, Young Adult)

A randomized, double-blind, phase 2b study to investigate the  efficacy, safety, tolerability and pharmacokinetics of a  single-dose regimen of ferroquine with artefenomel in adults and  children with uncomplicated Plasmodium falciparum malaria

Mehreen S Datoo; Magloire H Natama; Athanase Somé; Ousmane Traoré; Toussaint Rouamba; Duncan Bellamy; Prisca Yameogo; Daniel Valia; Moubarak Tegneri; Florence Ouedraogo; Rachidatou Soma; Seydou Sawadogo; Faizatou Sorgho; Karim Derra; Eli Rouamba; Benedict Orindi; Fernando Ramos Lopez; Amy Flaxman; Federica Cappuccini; Reshma Kailath; Sean Elias; Ekta Mukhopadhyay; Andres Noe; Matthew Cairns; Alison Lawrie; Rachel Roberts; Innocent Valéa; Hermann Sorgho; Nicola Williams; Gregory Glenn; Louis Fries; Jenny Reimer; Katie J Ewer; Umesh Shaligram; Adrian V S Hill; Halidou Tinto

Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial (Journal Article)

In: Lancet, 397 (10287), pp. 1809–1818, 2021, ISSN: 1474-547X 0140-6736, (Copyright © 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved. PMID: 33964223 PMCID: PMC8121760).

(Abstract | Links | BibTeX | Altmetric | Tags: Adjuvants, Burkina Faso, Double-Blind Method, Falciparum/prevention & control, Female, Hepatitis B Surface Antigens, Humans, Immunogenicity, Immunologic/administration & dosage, Infant, Malaria, Malaria Vaccines/therapeutic use, Malaria/prevention & control, Male, Nanoparticles/administration & dosage, Proportional Hazards Models, Protozoan Proteins/immunology, Saponins/administration & dosage, Treatment Outcome, Vaccine, Vaccines, Virus-Like Particle/therapeutic use)

Efficacy of a low-dose candidate malaria vaccine, R21 in  adjuvant Matrix-M, with seasonal administration to children in  Burkina Faso: a randomised controlled trial

Toussaint Rouamba; Sékou Samadoulougou; Mady Ouédraogo; Hervé Hien; Halidou Tinto; Fati Kirakoya-Samadoulougou

Asymptomatic malaria and anaemia among pregnant women during high and low malaria transmission seasons in Burkina Faso: household-based cross-sectional surveys in Burkina Faso, 2013 and 2017 (Journal Article)

In: Malar. J., 20 (1), pp. 211, 2021, ISSN: 1475-2875.

(Abstract | Links | BibTeX | Altmetric | Tags: Adult, Anemia/epidemiology/parasitology, Asymptomatic carriage, Asymptomatic Infections/epidemiology, Burkina Faso/epidemiology, Community, Cross-Sectional Studies, Female, Haemoglobin, Humans, Malaria/epidemiology/parasitology, Parasitic/epidemiology/parasitology, Plasmodium, Pregnancy, Pregnancy Complications, Pregnant, Pregnant Women, Prevalence, Young Adult)

Asymptomatic malaria and anaemia among pregnant women during  high and low malaria transmission seasons in Burkina Faso:  household-based cross-sectional surveys in Burkina Faso, 2013  and 2017

Massa Dit Achille Bonko; Palpouguini Lompo; Marc Christian Tahita; Francois Kiemde; Ibrahima Karama; Athanase M Somé; Petra F Mens; Sandra Menting; Halidou Tinto; Henk D F H Schallig

Antibiotic susceptibility of Staphylococcus aureus and Streptococcus pneumoniae isolates from the nasopharynx of febrile children under 5 years in Nanoro, Burkina Faso (Journal Article)

In: Antibiotics (Basel), 10 (4), 2021, ISSN: 2079-6382, (PMID: 33920987 PMCID: PMC8071235).

(Abstract | Links | BibTeX | Altmetric | Tags: antibiotics, children; nasopharynx, resistance, Staphylococcus aureus, Streptococcus pneumoniae)

Antibiotic susceptibility of Staphylococcus aureus and  Streptococcus pneumoniae isolates from the nasopharynx of febrile  children under 5 years in Nanoro, Burkina Faso

Sabine Gies; Stephen A Roberts; Salou Diallo; Olga M Lompo; Halidou Tinto; Bernard J Brabin

Risk of malaria in young children after periconceptional iron supplementation (Journal Article)

In: Matern. Child Nutr., 17 (2), pp. e13106, 2021, ISSN: 1740-8709 1740-8695, (© 2020 The Authors. Maternal & Child Nutrition published by John Wiley & Sons Ltd. PMID: 33236840 PMCID: PMC7988873).

(Abstract | Links | BibTeX | Altmetric | Tags: Burkina Faso, child iron, Dietary Supplements/analysis, Female, Folic Acid, Humans, Infant, Malaria, Newborn, periconceptional, placenta, Pregnancy, Premature Birth, Preschool)

Risk of malaria in young children after periconceptional iron  supplementation

Engelbert A Nonterah; Michiel L Bots; Abraham Oduro; Godfred Agongo; Cassandra C Soo; Lisa K Micklesfield; Felistas Mashinya; Palwendé R Boua; Shukri F Mohamed; Alisha N Wade; Catherine Kyobutungi; Halidou Tinto; Shane A Norris; Stephen M Tollman; Mich`ele Ramsay; Diederick E Grobbee; Kerstin Klipstein-Grobusch; Nigel J Crowther; AWI-Gen; H3Africa Consortium

Adiposity phenotypes and subclinical atherosclerosis in adults from sub-Saharan Africa: An H3Africa AWI-gen study (Journal Article)

In: Glob. Heart, 16 (1), pp. 19, 2021, ISSN: 2211-8179 2211-8160, (Copyright: © 2021 The Author(s). PMID: 33833943 PMCID: PMC7977036).

(Abstract | Links | BibTeX | Altmetric | Tags: adiposity, Adult, Body Mass Index, cardiovascular disease, Carotid intima-media thickness, Cross-Sectional Studies, Female, Ghana, Humans, Male, Middle Aged, obesity, Obesity/complications/epidemiology, Phenotype, Risk Factors, sub-Saharan Africa, subclinical atherosclerosis)

Adiposity phenotypes and subclinical atherosclerosis in adults  from sub-Saharan Africa: An H3Africa AWI-gen study

Annelies Post; Berenger Kaboré; Joel Bognini; Salou Diallo; Palpouguini Lompo; Basile Kam; Natacha Herssens; Fred Opzeeland; Christa E Gaast-de Jongh; Jeroen D Langereis; Marien I Jonge; Janette Rahamat-Langendoen; Teun Bousema; Heiman Wertheim; Robert W Sauerwein; Halidou Tinto; Jan Jacobs; Quirijn Mast; Andre J Ven

Infection Manager System (IMS) as a new hemocytometry-based bacteremia detection tool: A diagnostic accuracy study in a malaria-endemic area of Burkina Faso (Journal Article)

In: PLoS Negl. Trop. Dis., 15 (3), pp. e0009187, 2021, ISSN: 1935-2735 1935-2727, (PMID: 33647009 PMCID: PMC7951874).

(Abstract | Links | BibTeX | Altmetric | Tags: Adolescent, Automation, Bacteremia/diagnosis, Burkina Faso, C-Reactive Protein/analysis, Child, Coinfection/diagnosis/microbiology/parasitology, Female, Fever of Unknown Origin/diagnosis, Humans, Infant, Laboratory/methods, Malaria/diagnosis, Male, Preschool, Procalcitonin/analysis, Prospective Studies, Sensitivity and Specificity, Software, Virus Diseases/diagnosis)

Infection Manager System (IMS) as a new hemocytometry-based  bacteremia detection tool: A diagnostic accuracy study in a  malaria-endemic area of Burkina Faso

Palpouguini Lompo; Marc Christian Tahita; Hermann Sorgho; William Kaboré; Adama Kazienga; Ashmed Cheick Bachirou Nana; Hamtandi Magloire Natama; Isidore Juste Ouindgueta Bonkoungou; Nicolas Barro; Halidou Tinto

Pathogens associated with acute diarrhea, and comorbidity with malaria among children under five years old in rural Burkina Faso (Journal Article)

In: Pan Afr. Med. J., 38 , pp. 259, 2021, ISSN: 1937-8688, (Copyright: Palpouguini Lompo et al. PMID: 34104307 PMCID: PMC8164431).

(Abstract | Links | BibTeX | Altmetric | Tags: Abdominal Pain/epidemiology, Acute Disease, bacteria, Burkina Faso, Burkina Faso/epidemiology, Child, Comorbidity, Diarrhea, Diarrhea/epidemiology/microbiology, Female, Fever/epidemiology, Giardiasis/epidemiology, Humans, Infant, infectious, Malaria, Malaria/epidemiology, Male, parasite, pathogens, Preschool, Prevalence, Risk Factors, rotavirus, Rotavirus Infections/epidemiology, Rural Population, Seasons, Vomiting/epidemiology)

Pathogens associated with acute diarrhea, and comorbidity with  malaria among children under five years old in rural Burkina  Faso

Hamatandi Magloire Natama; Eduard Rovira-Vallbona; Meryam Krit; Pieter Guetens; Hermann Sorgho; M Athanase Somé; Maminata Traoré-Coulibaly; Innocent Valéa; Petra F Mens; Henk D F H Schallig; Dirk Berkvens; Luc Kestens; Halidou Tinto; Anna Rosanas-Urgell

Genetic variation in the immune system and malaria susceptibility in infants: a nested case-control study in Nanoro, Burkina Faso (Journal Article)

In: Malar. J., 20 (1), pp. 94, 2021, ISSN: 1475-2875, (PMID: 33593344 PMCID: PMC7885350).

(Abstract | Links | BibTeX | Altmetric | Tags: Burkina Faso, Case-Control Studies, Cytokines, Falciparum/parasitology, Female, Genetic Predisposition to Disease/genetics, Humans, Immunity, Immunogenetic variants, Infant, Innate immunity, Innate/genetics, Malaria, Male, Plasmodium falciparum, Plasmodium falciparum/physiology)

Genetic variation in the immune system and malaria  susceptibility in infants: a nested case-control study in  Nanoro, Burkina Faso

Adama Gansané; Leah F Moriarty; Didier Ménard; Isidore Yerbanga; Esperance Ouedraogo; Paul Sondo; Rene Kinda; Casimir Tarama; Edwige Soulama; Madou Tapsoba; David Kangoye; Cheick Said Compaore; Ousmane Badolo; Blami Dao; Samuel Tchwenko; Halidou Tinto; Innocent Valea

Anti-malarial efficacy and resistance monitoring of artemether-lumefantrine and dihydroartemisinin-piperaquine shows inadequate efficacy in children in Burkina Faso, 2017-2018 (Journal Article)

In: Malar. J., 20 (1), pp. 48, 2021, ISSN: 1475-2875.

(Abstract | Links | BibTeX | Altmetric | Tags: Antimalarial, Antimalarials/pharmacology, Artemether, Artemether-lumefantrine, Artemisinins/pharmacology, Burkina Faso, Child, Dihydroartemisinin-piperaquine, Drug Resistance, Efficacy, Falciparum/drug therapy, Female, Lumefantrine Drug Combination/pharmacology, Malaria, Male, Plasmodium falciparum, Preschool, Quinolines/pharmacology)

Anti-malarial efficacy and resistance monitoring of  artemether-lumefantrine and dihydroartemisinin-piperaquine shows  inadequate efficacy in children in Burkina Faso, 2017-2018

Paul Sondo; Biebo Bihoun; Marc Christian Tahita; Karim Derra; Toussaint Rouamba; Seydou Nakanabo Diallo; Adama Kazienga; Hamidou Ilboudo; Innocent Valea; Zekiba Tarnagda; Hermann Sorgho; Thierry Lef`evre; Halidou Tinto

Plasmodium falciparum gametocyte carriage in symptomatic patients shows significant association with genetically diverse infections, anaemia, and asexual stage density (Journal Article)

In: Malar. J., 20 (1), pp. 31, 2021, ISSN: 1475-2875, (PMID: 33413393 PMCID: PMC7791700).

(Abstract | Links | BibTeX | Altmetric | Tags: Anemia/epidemiology/parasitology, Burkina Faso/epidemiology, Falciparum/epidemiology/parasitology, Gametocyte, Humans, Malaria, msp1, msp2, Multiplicity of infection, Plasmodium falciparum, Plasmodium falciparum/physiology)

Plasmodium falciparum gametocyte carriage in symptomatic  patients shows significant association with genetically diverse  infections, anaemia, and asexual stage density

2020

André Lin Ouédraogo; Julie Zhang; Halidou Tinto; Innocent Valéa; Edward A Wenger

A microplanning model to improve door-to-door health service delivery: the case of Seasonal Malaria Chemoprevention in Sub-Saharan African villages (Journal Article)

In: BMC Health Serv. Res., 20 (1), pp. 1128, 2020, ISSN: 1472-6963, (PMID: 33287825 PMCID: PMC7720067).

(Abstract | Links | BibTeX | Altmetric | Tags: Africa South of the Sahara/epidemiology, Antimalarials/therapeutic use, Burkina Faso, Chemoprevention, Child, CHW, Community health worker, Door-to-door, Health Services, Humans, Malaria, Malaria/drug therapy/epidemiology/prevention & control, Microplanning, Model, Satellite imagerySeasonal malaria chemoprevention, Seasons, SMC)

A microplanning model to improve door-to-door health service  delivery: the case of Seasonal Malaria Chemoprevention in  Sub-Saharan African villages

Laura Skrip; Karim Derra; Mikaila Kaboré; Navideh Noori; Adama Gansané; Innocent Valéa; Halidou Tinto; Bicaba W Brice; Mollie Van Gordon; Brittany Hagedorn; Hervé Hien; Benjamin M Althouse; Edward A Wenger; André Lin Ouédraogo

Clinical management and mortality among COVID-19 cases in sub-Saharan Africa: A retrospective study from Burkina Faso and simulated case analysis (Journal Article)

In: Int. J. Infect. Dis., 101 , pp. 194–200, 2020, ISSN: 1878-3511 1201-9712, (Copyright © 2020 The Authors. Published by Elsevier Ltd.. All rights reserved. PMID: 32987177 PMCID: PMC7518969).

(Abstract | Links | BibTeX | Altmetric | Tags: Adolescent, Adult, Africa South of the Sahara, Aged, Antiviral Agents/administration & dosage, Asia/epidemiology, Burkina Faso, Burkina Faso/epidemiology, Child, Clinical management of SARS-CoV-2 infection: convalescent plasma, COVID-19/drug therapy/epidemiology/mortality/therapy, Europe/epidemiology, Female, Health systems strengthening, Humans, Immunization, Infant, Male, Mortality, Oxygen therapy, Pandemics, Passive, Preschool, Retrospective Studies, SARS-CoV-2 infection, SARS-CoV-2/drug effects/physiology, sub-Saharan Africa, Young Adult)

Clinical management and mortality among COVID-19 cases in  sub-Saharan Africa: A retrospective study from Burkina Faso and  simulated case analysis

Chetan E Chitnis; David Schellenberg; Johan Vekemans; Edwin J Asturias; Philip Bejon; Katharine A Collins; Brendan S Crabb; Socrates Herrera; Miriam Laufer; N Regina Rabinovich; Meta Roestenberg; Adelaide Shearley; Halidou Tinto; Marian Wentworth; Kate O’Brien; Pedro Alonso

Building momentum for malaria vaccine research and development: key considerations (Journal Article)

In: Malar. J., 19 (1), pp. 421, 2020, ISSN: 1475-2875, (PMID: 33228666 PMCID: PMC7682132).

(Abstract | Links | BibTeX | Altmetric | Tags: Control; Elimination; Malaria; Research and development; Vaccine)

Building momentum for malaria vaccine research and development:  key considerations

Hamtandi Magloire Natama; Rouamba Toussaint; Djamina Line Cerine Bazié; Sékou Samadoulougou; Maminata Coulibaly-Traoré; Halidou Tinto; Fati Kirakoya-Samadoulougou

Prevalence and factors associated with carriage of Pfmdr1 polymorphisms among pregnant women receiving intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) and artemether-lumefantrine for malaria treatment in Burkina Faso (Journal Article)

In: Malar. J., 19 (1), pp. 399, 2020.

(Abstract | BibTeX | Tags: Artemether-lumefantrine; Malaria; Pregnancy; pfmdr1 mutations)

Serge Henri Zango; Moussa Lingani; Innocent Valea; Ouindpanga Sékou Samadoulougou; Biebo Bihoun; Toussaint Rouamba; Karim Derra; Eli Rouamba; Phillipe Donnen; Michele Dramaix; Halidou Tinto; Annie Robert

Malaria and curable sexually transmitted infections in pregnant women: A two-years observational study in rural Burkina Faso (Journal Article)

In: PLoS One, 15 (11), pp. e0242368, 2020.

(Abstract | BibTeX | Tags: )

Olawale Salami; Philip Horgan; Catrin E Moore; Abhishek Giri; Asadu Sserwanga; Ashish Pathak; Buddha Basnyat; Francois Kiemde; Frank Smithuis; Freddy Kitutu; Gajanan Phutke; Halidou Tinto; Heidi Hopkins; James Kapisi; Myo Maung Maung Swe; Neelam Taneja; Rita Baiden; Shanta Dutta; Adelaide Compaore; David Kaawa-Mafigiri; Rashida Hussein; Summita Udas Shakya; Vida Kukula; Stefano Ongarello; Anjana Tomar; Sarabjit S Chadha; Kamini Walia; Cassandra Kelly-Cirino; Piero Olliaro

Impact of a package of diagnostic tools, clinical algorithm, and training and communication on outpatient acute fever case management in low- and middle-income countries: protocol for a randomized controlled trial (Journal Article)

In: Trials, 21 (1), pp. 974, 2020.

(Abstract | BibTeX | Tags: Antibiotic prescription; Antimicrobial resistance; Febrile illness; Outpatient fever management; Randomized controlled trial)

Berenger Kaboré; Annelies Post; Mike L T Berendsen; Salou Diallo; Palpouguini Lompo; Karim Derra; Eli Rouamba; Jan Jacobs; Halidou Tinto; Quirijn Mast; Andre J Ven

Red blood cell homeostasis in children and adults with and without asymptomatic malaria infection in Burkina Faso (Journal Article)

In: PLoS One, 15 (11), pp. e0242507, 2020.

(Abstract | BibTeX | Tags: )

197 entries « 2 of 10 »