| Bryony Simmons, Elisa Sicuri, Jane Carter, Asrat Hailu, Francois Kiemde, Petra Mens, Davis Mumbengegwi, Bakri Nour, René Paulussen, Henk Schallig, Halidou Tinto, Norbert Dijk, Lesong Conteh Defining a malaria diagnostic pathway from innovation to adoption: Stakeholder perspectives on data and evidence gaps Journal Article In: PLOS global public health, vol. 4, iss. 5, 2024, ISSN: 2767-3375. @article{Simmons2024,
title = {Defining a malaria diagnostic pathway from innovation to adoption: Stakeholder perspectives on data and evidence gaps},
author = {Bryony Simmons and Elisa Sicuri and Jane Carter and Asrat Hailu and Francois Kiemde and Petra Mens and Davis Mumbengegwi and Bakri Nour and Ren\'{e} Paulussen and Henk Schallig and Halidou Tinto and Norbert Dijk and Lesong Conteh},
url = {https://pubmed.ncbi.nlm.nih.gov/38753739/},
doi = {10.1371/JOURNAL.PGPH.0002957},
issn = {2767-3375},
year = {2024},
date = {2024-01-01},
journal = {PLOS global public health},
volume = {4},
issue = {5},
publisher = {PLOS Glob Public Health},
abstract = {Malaria, a major global health concern, requires effective diagnostic tools for patient care, disease control, and elimination. The pathway from concept to the adoption of diagnostic products is complex, involving multiple steps and stakeholders. To map this process, our study introduces a malaria-specific diagnostic pathway, synthesising existing frameworks with expert insights. Comprising six major stages and 31 related activities, the pathway retains the core stages from existing frameworks and integrates essential malaria diagnostic activities, such as WHO prequalification processes, global stakeholder involvement, and broader health systems considerations. To understand the scope and availability of evidence guiding the activities along this pathway, we conducted an online survey with 113 participants from various stages of the malaria diagnostic pathway. The survey assessed perceptions on four critical attributes of evidence: clear requirements, alignment with user needs, accuracy and reliability, and public and free availability. It also explored the types of evidence used and the challenges and potential solutions related to evidence generation and use. Respondents reported using a broad range of formal and informal data sources. Findings indicated differing levels of agreement on the attributes across pathway stages, with notable challenges in the Approvals and Manufacturing stage and consistent concerns regarding the public availability of data/evidence. The study offers valuable insights for optimising evidence generation and utilisation across the malaria diagnostic pathway. It highlights the need for enhanced stakeholder collaboration, improved data availability, and increased funding to support effective evidence generation, sharing, and use. We propose actionable solutions, including the use of public data repositories, progressive data sharing policies, open-access publishing, capacity-building initiatives, stakeholder engagement},
keywords = {Bryony Simmons, doi:10.1371/journal.pgph.0002957, Elisa Sicuri, Lesong Conteh, MEDLINE, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, PMC11098419, pmid:38753739, PubMed Abstract},
pubstate = {published},
tppubtype = {article}
}
Malaria, a major global health concern, requires effective diagnostic tools for patient care, disease control, and elimination. The pathway from concept to the adoption of diagnostic products is complex, involving multiple steps and stakeholders. To map this process, our study introduces a malaria-specific diagnostic pathway, synthesising existing frameworks with expert insights. Comprising six major stages and 31 related activities, the pathway retains the core stages from existing frameworks and integrates essential malaria diagnostic activities, such as WHO prequalification processes, global stakeholder involvement, and broader health systems considerations. To understand the scope and availability of evidence guiding the activities along this pathway, we conducted an online survey with 113 participants from various stages of the malaria diagnostic pathway. The survey assessed perceptions on four critical attributes of evidence: clear requirements, alignment with user needs, accuracy and reliability, and public and free availability. It also explored the types of evidence used and the challenges and potential solutions related to evidence generation and use. Respondents reported using a broad range of formal and informal data sources. Findings indicated differing levels of agreement on the attributes across pathway stages, with notable challenges in the Approvals and Manufacturing stage and consistent concerns regarding the public availability of data/evidence. The study offers valuable insights for optimising evidence generation and utilisation across the malaria diagnostic pathway. It highlights the need for enhanced stakeholder collaboration, improved data availability, and increased funding to support effective evidence generation, sharing, and use. We propose actionable solutions, including the use of public data repositories, progressive data sharing policies, open-access publishing, capacity-building initiatives, stakeholder engagement |
