Publications

@article{Mirzaev2024,

title = {Systematic review and meta-analysis of hepatitis E seroprevalence in Southeast Asia: a comprehensive assessment of epidemiological patterns},

author = {Ulugbek Khudayberdievich Mirzaev and Serge Ouoba and Ko Ko and Zayar Phyo and Chanroth Chhoung and Akuffo Golda Ataa and Aya Sugiyama and Tomoyuki Akita and Junko Tanaka},

url = {https://pubmed.ncbi.nlm.nih.gov/38789918/},

doi = {10.1186/S12879-024-09349-2},

issn = {1471-2334},

year  = {2024},

date = {2024-01-01},

journal = {BMC infectious diseases},

volume = {24},

issue = {1},

publisher = {BMC Infect Dis},

abstract = {The burden of hepatitis E in Southeast Asia is substantial, influenced by its distinct socio-economic and environmental factors, as well as variations in healthcare systems. The aim of this study was to assess the pooled seroprevalence of hepatitis E across countries within the Southeast Asian region by the UN division. The study analyzed 66 papers across PubMed, Web of Science, and Scopus databases, encompassing data from of 44,850 individuals focusing on anti-HEV seroprevalence. The investigation spanned nine countries, excluding Brunei and East Timor due to lack of data. The pooled prevalence of anti-HEV IgG was determined to be 21.03%, with the highest prevalence observed in Myanmar (33.46%) and the lowest in Malaysia (5.93%). IgM prevalence was highest in Indonesia (12.43%) and lowest in Malaysia (0.91%). The study stratified populations into high-risk (farm workers, chronic patients) and low-risk groups (general population, blood donors, pregnant women, hospital patients). It revealed a higher IgG\textemdash28.9%, IgM\textemdash4.42% prevalence in the former group, while the latter group exhibited figures of 17.86% and 3.15%, respectively, indicating occupational and health-related vulnerabilities to HEV. A temporal analysis (1987\textendash2023), indicated an upward trend in both IgG and IgM prevalence, suggesting an escalating HEV burden. These findings contribute to a better understanding of HEV seroprevalence in Southeast Asia, shedding light on important public health implications and suggesting directions for further research and intervention strategies. Key points Research Question Investigate the seroprevalence of hepatitis E virus (HEV) in Southeast Asian countries focusing on different patterns, timelines, and population cohorts. Findings Sporadic Transmission of IgG and IgM Prevalence: • Pooled anti-HEV IgG prevalence: 21.03% • Pooled anti-HEV IgM prevalence: 3.49% Seroprevalence among specific groups: High-risk group (farm workers and chronic patients): • anti-HEV IgG: 28.9% • anti-HEV IgM: 4.42% Low-risk group (general population, blood donors, pregnant women, hospital patients): • anti-HEV IgG: 17.86% • anti-HEV IgM: 3.15% Temporal Seroprevalence of HEV: Anti-HEV IgG prevalence increased over decades (1987\textendash1999; 2000\textendash2010; 2011\textendash2023): 12.47%, 18.43%, 29.17% as an anti-HEV IgM prevalence: 1.92%, 2.44%, 5.27% Importance Provides a comprehensive overview of HEV seroprevalence in Southeast Asia. Highlights variation in seroprevalence among different population groups. Reveals increasing trend in HEV seroprevalence over the years. Distinguishes between sporadic and epidemic cases for a better understanding of transmission dynamics.},

keywords = {Asia, doi:10.1186/s12879-024-09349-2, Female, Hepatitis Antibodies* / blood, Hepatitis E virus* / immunology, Hepatitis E* / blood, Hepatitis E* / epidemiology, Humans, Immunoglobulin G* / blood, Immunoglobulin M* / blood, Junko Tanaka, Male, MEDLINE, Meta-Analysis, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, PMC11127338, pmid:38789918, Pregnancy, Prevalence, PubMed Abstract, Risk Factors, Serge Ouoba, Seroepidemiologic Studies, Southeastern / epidemiology, Systematic review, Ulugbek Khudayberdievich Mirzaev},

pubstate = {published},

tppubtype = {article}

}

@article{Bassinga2024,

title = {Prevalence of asymptomatic malaria at the communal level in Burkina Faso: an application of the small area estimation approach},

author = {Herv\'{e} Bassinga and Mady Ouedraogo and Kadari Cisse and Parfait Yira and Sibiri Cl\'{e}ment Ouedraogo and Abdou Nombr\'{e} and Wofom Lydie Marie Bernard Bance and Mathias Kuepie and Toussaint Rouamba},

url = {https://pubmed.ncbi.nlm.nih.gov/39155384/},

doi = {10.1186/S12963-024-00341-1},

issn = {1478-7954},

year  = {2024},

date = {2024-01-01},

journal = {Population health metrics},

volume = {22},

issue = {1},

publisher = {Popul Health Metr},

abstract = {Background: In malaria-endemic countries, asymptomatic carriers of plasmodium represent an important reservoir for malaria transmission. Estimating the burden at a fine scale and identifying areas at high risk of asymptomatic carriage are important to guide malaria control strategies. This study aimed to estimate the prevalence of asymptomatic carriage at the communal level in Burkina Faso, the smallest geographical entity from which a local development policy can be driven. Methods: The data used in this study came from several open sources: the 2018 Multiple Indicator Cluster Survey on Malaria and the 2019 general census of the population data and environmental. The analysis involved a total of 5489 children under 5 from the malaria survey and 293,715 children under 5 from the census. The Elbers Langjouw and Langjouw (ELL) approach is used to estimate the prevalence. This approach consists of including data from several sources (mainly census and survey data) in a statistical model to obtain predictive indicators at a sub-geographical level, which are not measured in the population census. The method achieves this by finding correlations between common census variables and survey data. Findings: The findings suggest that the spatial distribution of the prevalence of asymptomatic carriage is very heterogeneous across the communes. It varies from a minimum of 5.1% (95% CI 3.6\textendash6.5) in the commune of Bobo-Dioulasso to a maximum of 41.4% (95% CI 33.5\textendash49.4) in the commune of Djigou\'{e}. Of the 341 communes, 208 (61%) had prevalences above the national average of 20.3% (95% CI 18.8\textendash21.2). Contributions: This analysis provided commune-level estimates of the prevalence of asymptomatic carriage of plasmodium in Burkina Faso. The results of this analysis should help to improve planning of malaria control at the communal level in Burkina Faso.},

keywords = {Asymptomatic Infections / epidemiology, Burkina Faso / epidemiology, Carrier State / epidemiology, Child, doi:10.1186/s12963-024-00341-1, Female, Herv\'{e} Bassinga, Humans, Infant, Mady Ouedraogo, Malaria* / epidemiology, Male, MEDLINE, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, PMC11330607, pmid:39155384, Preschool, Prevalence, PubMed Abstract, Small-Area Analysis, Toussaint Rouamba},

pubstate = {published},

tppubtype = {article}

}

@article{Soumah2024,

title = {Prevalence of dermal trypanosomes in suspected and confirmed cases of gambiense human African trypanosomiasis in Guinea},

author = {Alseny M’Mah Soumah and Mariame Camara and Justin Windingoudi Kabor\'{e} and Ibrahim Sadissou and Hamidou Ilboudo and Christelle Travaill\'{e} and Oumou Camara and Magali Tichit and Jacques Kabor\'{e} and Salimatou Boiro and Aline Crouzols and Jean Marc Tsagmo Ngoune and David Hardy and A\"{i}ssata Camara and Vincent Jamonneau and Annette Macleod and Jean Mathieu Bart and Mamadou Camara and Bruno Bucheton and Brice Rotureau},

url = {https://pubmed.ncbi.nlm.nih.gov/39159265/},

doi = {10.1371/JOURNAL.PNTD.0012436},

issn = {1935-2735},

year  = {2024},

date = {2024-01-01},

journal = {PLoS neglected tropical diseases},

volume = {18},

issue = {8},

publisher = {PLoS Negl Trop Dis},

abstract = {The skin is an anatomical reservoir for African trypanosomes, yet the prevalence of extravascular parasite carriage in the population at risk of gambiense Human African Trypanosomiasis (gHAT) remains unclear. Here, we conducted a prospective observational cohort study in the HAT foci of Forecariah and Boffa, Republic of Guinea. Of the 18,916 subjects serologically screened for gHAT, 96 were enrolled into our study. At enrolment and follow-up visits, participants underwent a dermatological examination and had blood samples and superficial skin snip biopsies taken for examination by molecular and immuno-histological methods. In seropositive individuals, dermatological symptoms were significantly more frequent as compared to seronegative controls. Trypanosoma brucei DNA was detected in the blood of 67% of confirmed cases (22/33) and 9% of unconfirmed seropositive individuals (3/32). However, parasites were detected in the extravascular dermis of up to 71% of confirmed cases (25/35) and 41% of unconfirmed seropositive individuals (13/32) by PCR and/or immuno-histochemistry. Six to twelve months after treatment, trypanosome detection in the skin dropped to 17% of confirmed cases (5/30), whereas up to 25% of unconfirmed, hence untreated, seropositive individuals (4/16) were still found positive. Dermal trypanosomes were observed in subjects from both transmission foci, however, the occurrence of pruritus and the PCR positivity rates were significantly higher in unconfirmed seropositive individuals in Forecariah. The lower sensitivity of superficial skin snip biopsies appeared critical for detecting trypanosomes in the basal dermis. These results are discussed in the context of the planned elimination of gHAT.},

keywords = {Adolescent, Adult, African* / diagnosis, African* / epidemiology, African* / parasitology, Alseny M'mah Soumah, Brice Rotureau, Child, DNA, doi:10.1371/journal.pntd.0012436, Female, Guinea / epidemiology, Humans, Male, Mariame Camara, MEDLINE, Middle Aged, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, Observational Study, PMC11361743, pmid:39159265, Prevalence, Prospective Studies, Protozoan / genetics, PubMed Abstract, Skin* / parasitology, Skin* / pathology, Trypanosoma brucei gambiense* / isolation \& purification, Trypanosomiasis, Young Adult},

pubstate = {published},

tppubtype = {article}

}

@article{Phyo2024,

title = {Intermediate hepatitis C virus (HCV) endemicity and its genotype distribution in Myanmar: A systematic review and meta-analysis},

author = {Zayar Phyo and Ko Ko and Serge Ouoba and Aya Sugiyama and Ulugbek Khudayberdievich Mirzaev and Golda Ataa Akuffo and Chanroth Chhoung and Tomoyuki Akita and Junko Tanaka},

url = {https://pubmed.ncbi.nlm.nih.gov/39298388/},

doi = {10.1371/JOURNAL.PONE.0307872},

issn = {1932-6203},

year  = {2024},

date = {2024-01-01},

journal = {PloS one},

volume = {19},

issue = {9},

publisher = {PLoS One},

abstract = {Background Comprehensive details on Hepatitis C virus (HCV) infection in Myanmar are lacking. This study determined the prevalence of HCV antibodies and ribonucleic acid (RNA) and the distribution of HCV genotypes across different populations in Myanmar from 1990 to 2023. Material and methods A systematic search in PubMed, Web of Science, Scopus, and local journals identified studies reporting on HCV antibodies, RNA, and genotypes, excluding clinical research related to liver disease prognosis. Screening and data extraction was done by two authors and study populations were categorized into low-risk, high-risk, liver disease patients, and refugees outside the country. The pooled prevalence was performed by Dersimonian and Laird method using the R program. The publication bias was shown by funnel plot, the Egger test was used to assess the symmetry of the plot, and the heterogeneity was examined by the Cochran Q test and I2 index. Results Out of 135 reports screened for eligibility, 35 reports comprising 51 studies were included in which 33 studies provided data on HCV seroprevalence in 685,403 individuals, 8 studies reported HCV RNA prevalence in 25,018 individuals, and 10 studies examined HCV genotypes in 1,845 individuals. The pooled seroprevalence of HCV among low-risk, high-risk, liver disease patients and refugees were 2.18%, 37.07%, 33.84%, and 2.52% respectively. HCV RNA-positive rates in these groups were 1.40%, 5.25%, 24.96%, and 0.84% respectively. Seroprevalence studies showed publication bias (Egger test},

keywords = {doi:10.1371/journal.pone.0307872, Endemic Diseases, Genotype*, Hepacivirus* / genetics, Hepacivirus* / isolation \& purification, Hepatitis C* / epidemiology, Hepatitis C* / virology, Humans, Junko Tanaka, Ko Ko, MEDLINE, Meta-Analysis, Myanmar / epidemiology, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, PMC11412534, pmid:39298388, Prevalence, PubMed Abstract, RNA, Seroepidemiologic Studies, Systematic review, Viral / genetics, Zayar Phyo},

pubstate = {published},

tppubtype = {article}

}

@article{Micklesfield2023,

title = {Identifying the prevalence and correlates of multimorbidity in middle-aged men and women: a cross-sectional population-based study in four African countries},

author = {Lisa K. Micklesfield and Richard Munthali and Godfred Agongo and Gershim Asiki and Palwende Boua and Solomon S. R. Choma and Nigel J. Crowther and June Fabian and Francesc Xavier G\'{o}mez-Oliv\'{e} and Chodziwadziwa Kabudula and Eric Maimela and Shukri F. Mohamed and Engelbert A. Nonterah and Frederick J. Raal and Hermann Sorgho and Furahini D. Tluway and Alisha N. Wade and Shane A. Norris and Michele Ramsay},

url = {https://pubmed.ncbi.nlm.nih.gov/36918238/},

doi = {10.1136/BMJOPEN-2022-067788},

issn = {2044-6055},

year  = {2023},

date = {2023-01-01},

journal = {BMJ open},

volume = {13},

issue = {3},

publisher = {BMJ Open},

abstract = {Objectives To determine the prevalence of multimorbidity, to identify which chronic conditions cluster together and to identify factors associated with a greater risk for multimorbidity in sub-Saharan Africa (SSA). Design Cross-sectional, multicentre, population-based study. Setting Six urban and rural communities in four sub-Saharan African countries. Participants Men (n=4808) and women (n=5892) between the ages of 40 and 60 years from the AWI-Gen study. Measures Sociodemographic and anthropometric data, and multimorbidity as defined by the presence of two or more of the following conditions: HIV infection, cardiovascular disease, chronic kidney disease, asthma, diabetes, dyslipidaemia, hypertension. Results Multimorbidity prevalence was higher in women compared with men (47.2% vs 35%), and higher in South African men and women compared with their East and West African counterparts. The most common disease combination at all sites was dyslipidaemia and hypertension, with this combination being more prevalent in South African women than any single disease (25% vs 21.6%). Age and body mass index were associated with a higher risk of multimorbidity in men and women; however, lifestyle correlates such as smoking and physical activity were different between the sexes. Conclusions The high prevalence of multimorbidity in middle-aged adults in SSA is of concern, with women currently at higher risk. This prevalence is expected to increase in men, as well as in the East and West African region with the ongoing epidemiological transition. Identifying common disease clusters and correlates of multimorbidity is critical to providing effective interventions.},

keywords = {{Adult, Africa South of the Sahara / epidemiology, CollabAuthor(name='as members of AWI-Gen and the H3Africa Consortium', Cross-Sectional Studies, Dyslipidemias* / epidemiology, Extramural, Female, HIV Infections*, Humans, Hypertension* / epidemiology, Lisa K Micklesfield, Male, MEDLINE, Middle Aged, Multimorbidity, N.I.H., National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, Non-U.S. Gov't, PMC10016250, Prevalence, PubMed Abstract, Research Support, Richard Munthali, Risk Factors, Sex Factors},

pubstate = {published},

tppubtype = {article}

}

@article{Ouoba2023,

title = {Intermediate hepatitis B virus infection prevalence among 1622 pregnant women in rural Burkina Faso and implications for mother-to-child transmission},

author = {Serge Ouoba and Ko Ko and Moussa Lingani and Shintaro Nagashima and Alice N. Guingan\'{e} and E. Bunthen and Md Razeen Ashraf Hussain and Aya Sugiyama and Tomoyuki Akita and Masayuki Ohisa and Moussa Abdel Sanou and Ousmane Traore and Job Wilfried Nassa and Maimouna Sanou and Kazuaki Takahashi and Halidou Tinto and Junko Tanaka},

url = {https://pubmed.ncbi.nlm.nih.gov/37059812/},

doi = {10.1038/S41598-023-32766-3},

issn = {2045-2322},

year  = {2023},

date = {2023-01-01},

journal = {Scientific reports},

volume = {13},

issue = {1},

publisher = {Sci Rep},

abstract = {In highly endemic countries for hepatitis B virus (HBV) infection, childhood infection, including mother-to-child transmission (MTCT), represents the primary transmission route. High maternal DNA level (viral load ≥ 200,000 IU/mL) is a significant factor for MTCT. We investigated the prevalence of HBsAg, HBeAg, and high HBV DNA among pregnant women in three hospitals in Burkina Faso and assessed the performance of HBeAg to predict high viral load. Consenting pregnant women were interviewed on their sociodemographic characteristics and tested for HBsAg by a rapid diagnostic test, and dried blood spot (DBS) samples were collected for laboratory analyses. Of the 1622 participants, HBsAg prevalence was 6.5% (95% CI, 5.4\textendash7.8%). Among 102 HBsAg-positive pregnant women in DBS samples, HBeAg was positive in 22.6% (95% CI, 14.9\textendash31.9%), and viral load was quantified in 94 cases, with 19.1% having HBV DNA ≥ 200,000 IU/mL. HBV genotypes were identified in 63 samples and predominant genotypes were E (58.7%) and A (36.5%). The sensitivity of HBeAg by using DBS samples to identify high viral load in the 94 cases was 55.6%, and the specificity was 86.8%. These findings highlight the need to implement routine HBV screening and effective MTCT risk assessment for all pregnant women in Burkina Faso to enable early interventions that can effectively reduce MTCT.},

keywords = {Burkina Faso / epidemiology, Child, DNA, doi:10.1038/s41598-023-32766-3, Female, Hepatitis B e Antigens, Hepatitis B Surface Antigens, Hepatitis B virus / genetics, Hepatitis B* / diagnosis, Humans, Infectious Disease Transmission, Infectious* / epidemiology, Junko Tanaka, Ko Ko, MEDLINE, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, Non-U.S. Gov't, PMC10103033, pmid:37059812, Pregnancy, Pregnancy Complications, Pregnant Women, Prevalence, PubMed Abstract, Research Support, Serge Ouoba, Vertical / prevention \& control, Viral / genetics},

pubstate = {published},

tppubtype = {article}

}

@article{Wade2023,

title = {Diabetes care cascade and associated factors in 10 700 middle-aged adults in four sub-Saharan African countries: a cross-sectional study},

author = {Alisha N. Wade and Innocent Maposa and Godfred Agongo and Gershim Asiki and Palwende Boua and Solomon S. R. Choma and F. Xavier G\'{o}mez-Oliv\'{e} and Eric Maimela and Lisa K. Micklesfield and Shukri F. Mohamed and Engelbert A. Nonterah and Shane A. Norris and Hermann Sorgho and Michele Ramsay and Nigel J. Crowther},

url = {https://pubmed.ncbi.nlm.nih.gov/37105688/},

doi = {10.1136/BMJOPEN-2022-069193},

issn = {2044-6055},

year  = {2023},

date = {2023-01-01},

journal = {BMJ open},

volume = {13},

issue = {4},

publisher = {BMJ Open},

abstract = {Objectives We investigated progression through the care cascade and associated factors for people with diabetes in sub-Saharan Africa to identify attrition stages that may be most appropriate for targeted intervention. Design Cross-sectional study. Setting Community-based study in four sub-Saharan African countries. Participants 10 700 individuals, aged 40-60 years. Primary and secondary outcome measures The primary outcome measure was the diabetes cascade of care defined as the age-adjusted diabetes prevalence (self-report of diabetes, fasting plasma glucose (FPG) ≥7 mmol/L or random plasma glucose ≥11.1 mmol/L) and proportions of those who reported awareness of having diabetes, ever having received treatment for diabetes and those who achieved glycaemic control (FPG \<7.2 mmol/L). Secondary outcome measures were factors associated with having diabetes and being aware of the diagnosis. Results Diabetes prevalence was 5.5% (95% CI 4.4% to 6.5%). Approximately half of those with diabetes were aware (54%; 95% CI 50% to 58%); 73% (95% CI 67% to 79%) of aware individuals reported ever having received treatment. However, only 38% (95% CI 30% to 46%) of those ever having received treatment were adequately controlled. Increasing age (OR 1.1; 95% CI 1.0 to 1.1), urban residence (OR 2.3; 95% CI 1.6 to 3.5), hypertension (OR 1.9; 95% CI 1.5 to 2.4), family history of diabetes (OR 3.9; 95% CI 3.0 to 5.1) and measures of central adiposity were associated with higher odds of having diabetes. Increasing age (OR 1.1; 95% CI 1.0 to 1.1), semi-rural residence (OR 2.5; 95% CI 1.1 to 5.7), secondary education (OR 2.4; 95% CI 1.2 to 4.9), hypertension (OR 1.6; 95% CI 1.0 to 2.4) and known HIV positivity (OR 2.3; 95% CI 1.2 to 4.4) were associated with greater likelihood of awareness of having diabetes. Conclusions There is attrition at each stage of the diabetes care cascade in sub-Saharan Africa. Public health strategies should target improving diagnosis in high-risk individuals and intensifying therapy in individuals treated for diabetes.},

keywords = {{Adult, Africa South of the Sahara / epidemiology, Alisha N Wade, Blood Glucose, CollabAuthor(name='AWIGen and the H3Africa Consortium', Cross-Sectional Studies, Diabetes Mellitus* / epidemiology, Diabetes Mellitus* / therapy, Extramural, Humans, Hypertension* / epidemiology, Innocent Maposa, MEDLINE, Middle Aged, N.I.H., National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, PMC10151877, Prevalence, PubMed Abstract, Research Support},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis},

author = {Anna Maria Eijk and Kasia Stepniewska and Jenny Hill and Steve M. Taylor and Stephen J. Rogerson and Gilles Cottrell and R. Matthew Chico and Julie R. Gutman and Halidou Tinto and Holger W. Unger and Stephanie K. Yanow and Steven R. Meshnick and Feiko O. Kuile and Alfredo Mayor and Steve M. Taylor and Stephen J. Rogerson and R. Matthew Chico and Julie R. Gutman and Hallidou Tinto and Holger W. Unger and Stephanie K. Yanow and Manfred Accrombessi and Ayola A. Adegnika and Rukhsana Ahmed and Eliana Mar\'{i}a Arango-Fl\'{o}rez and Myriam Arevalo-Herrera and Emmanual Arinaitwe and Paulo Arnaldo and Per Ashorn and Ulla Ashorn and Azucena Bardaji and Inoni Betuela and Praveen K. Bharti and Francis Bohissou and Camila B\^{o}tto-Menezes and Vera Braun and Valerie Briand and Jessica Briggs and Mar\'{i}a Eugenia Castellanos and Daniel Chandramohan and Enesia Banda Chaponda and Chetan Chitnis and Lauren M. Cohee and Michel Cot and Umberto d'Alessandro and Lise Denoeud-Ndam and Meghna Desai and Alassane Dicko and Xavier Ding and Grant Dorsey and Patrick E. Duffy and Maha A. Elbadry and Sonia M. Enosse and Yue Fan and Nadine Fievet and Michal Fried and Blaise Genton and Raquel Gonzalez and Brian Greenwood and Linda Kalilani and Johanna H. Kattenberg and Kassoum Kayentao and Carole Khairallah and Christopher L. King and Dhanpat Kumar Kochar and Swati Kochar and Felix Koukouikila-Koussounda and Sarah H. Landis and Miriam K. Laufer and Rose F. Leke and Eusebio Macete and Sonia Maculuve and Mwayiwawo Madanitsa and Almahamoudou Mahamar and Ken Maleta and Indu Malhotra and Rella Zoleko Manego and Flor Ernestina Martinez-Espinosa and Achille Massougbodji and Don Mathanga and Michela Menegon and Clara Menendez and Petra Mens and Martin Meremikwu and Frank P. Mockenhaupt and Ghyslain Mombo-Ngoma and Dominic Mosha and Ivo Mueller and Alain Nahum and Paul Natureeba and Nicaise Ndam and Francine Ntoumi and Olabisi A. Oduwole and Bernard A. Okech and Maria Ome-Kaius and Kephas Otieno and Norma Padilla and Michal Ramharter and Rosemary Rochford and Anna Rosanas-Urgell and Maria Ruperez and Katherine R. Sabourin and Sergi Sanz and Henk D. Schallig and Susana Scott and Esperanca Sevene and Carlo Severini and Harry Tagbor and Diane Wallace Taylor and Maminata Traore Coulibaly and Ana Vasquez and Annie Walker-Abbey and Blair J. Wylie and Djimon M. Zannou and Stephen R. Meshnick},

url = {https://pubmed.ncbi.nlm.nih.gov/37276878/},

doi = {10.1016/S2214-109X(23)00194-8},

issn = {2214-109X},

year  = {2023},

date = {2023-01-01},

journal = {The Lancet. Global health},

volume = {11},

issue = {7},

pages = {e1061-e1074},

publisher = {Lancet Glob Health},

abstract = {Background: Malaria infections during pregnancy can cause adverse birth outcomes, yet many infections are undetected by microscopy. We aimed to describe the epidemiology of submicroscopic malaria infections in pregnant women in Asia, the Americas, and Africa using aggregated and individual participant data (IPD). Methods: For this systematic review and meta-analysis, studies (published Jan 1, 1997 to Nov 10, 2021) with information on both microscopic and submicroscopic infections during pregnancy from Asia, the Americas, or Africa, identified in the Malaria-in-Pregnancy Library, were eligible. Studies (or subgroups or study groups) that selected participants on the basis of the presence of fever or a positive blood smear were excluded to avoid selection bias. We obtained IPD (when available) and aggregated data. Estimates of malaria transmission intensity and sulfadoxine\textendashpyrimethamine resistance, matched by study location and year, were obtained using publicly available data. One-stage multivariable logit and multinomial models with random intercepts for study site were used in meta-analysis to assess prevalence of and risk factors for submicroscopic infections during pregnancy and at delivery. This study is registered with PROSPERO, number CRD42015027342. Findings: The search identified 87 eligible studies, 68 (78%) of which contributed to the analyses. Of these 68 studies, 45 (66%) studies contributed IPD (48 869 participants) and 23 (34%) studies contributed aggregated data (11 863 participants). During pregnancy, median prevalence estimates were 13·5% (range 0·0\textendash55·9, 66 substudies) for submicroscopic and 8·0% (0·0\textendash50·6, 66 substudies) for microscopic malaria. Among women with positive Plasmodium nucleic acid amplification tests (NAATs), the median proportion of submicroscopic infections was 58·7% (range 0·0\textendash100); this proportion was highest in the Americas (73·3%, 0·0\textendash100), followed by Asia (67·2%, 36·4\textendash100) and Africa (56·5%, 20·5\textendash97·7). In individual patient data analysis, compared with women with no malaria infections, those with submicroscopic infections were more likely to present with fever in Africa (adjusted odds ratio 1·32, 95% CI 1·02\textendash1·72; p=0·038) but not in other regions. Among women with NAAT-positive infections in Asia and the Americas, Plasmodium vivax infections were more likely to be submicroscopic than Plasmodium falciparum infections (3·69, 2·45\textendash5·54; p\<0·0001). Risk factors for submicroscopic infections among women with NAAT-positive infections in Africa included older age (age ≥30 years), multigravidity, and no HIV infection. Interpretation: During pregnancy, submicroscopic infections are more common than microscopic infections and are associated with fever in Africa. Malaria control in pregnancy should target both microscopic and submicroscopic infections. Funding: Bill \& Melinda Gates Foundation through the Worldwide Antimalarial Resistance Network.},

keywords = {{Adult, Anna Maria van Eijk, Antimalarials* / therapeutic use, Author(firstnames='Achille', Author(firstnames='Alain', Author(firstnames='Alassane', Author(firstnames='Alfredo', Author(firstnames='Almahamoudou', Author(firstnames='Ana', Author(firstnames='Anna', Author(firstnames='Annie', Author(firstnames='Ayola A', Author(firstnames='Azucena', Author(firstnames='Bernard A', Author(firstnames='Blair J', Author(firstnames='Blaise', Author(firstnames='Brian', Author(firstnames='Camila', Author(firstnames='Carlo', Author(firstnames='Carole', Author(firstnames='Chetan', Author(firstnames='Christopher L', Author(firstnames='Clara', Author(firstnames='Daniel', Author(firstnames='Dhanpat Kumar', Author(firstnames='Diane Wallace', Author(firstnames='Djimon M', Author(firstnames='Dominic', Author(firstnames='Don', Author(firstnames='Eliana Mar\'{i}a', Author(firstnames='Emmanual', Author(firstnames='Enesia Banda', Author(firstnames='Esperanca', Author(firstnames='Eusebio', Author(firstnames='Feiko O', Author(firstnames='Felix', Author(firstnames='Flor Ernestina', Author(firstnames='Francine', Author(firstnames='Francis', Author(firstnames='Frank P', Author(firstnames='Ghyslain', Author(firstnames='Gilles', Author(firstnames='Grant', Author(firstnames='Hallidou', Author(firstnames='Harry', Author(firstnames='Henk D', Author(firstnames='Holger W', Author(firstnames='Indu', Author(firstnames='Inoni', Author(firstnames='Ivo', Author(firstnames='Jenny', Author(firstnames='Jessica', Author(firstnames='Johanna H', Author(firstnames='Julie R', Author(firstnames='Kasia', Author(firstnames='Kassoum', Author(firstnames='Katherine R', Author(firstnames='Ken', Author(firstnames='Kephas', Author(firstnames='Lauren M', Author(firstnames='Linda', Author(firstnames='Lise', Author(firstnames='Maha A', Author(firstnames='Maminata', Author(firstnames='Manfred', Author(firstnames='Mar\'{i}a Eugenia', Author(firstnames='Maria', Author(firstnames='Martin', Author(firstnames='Meghna', Author(firstnames='Michal', Author(firstnames='Michel', Author(firstnames='Michela', Author(firstnames='Miriam K', Author(firstnames='Mwayiwawo', Author(firstnames='Myriam', Author(firstnames='Nadine', Author(firstnames='Nicaise', Author(firstnames='Norma', Author(firstnames='Olabisi A', Author(firstnames='Patrick E', Author(firstnames='Paul', Author(firstnames='Paulo', Author(firstnames='Per', Author(firstnames='Petra', Author(firstnames='Praveen K', Author(firstnames='R Matthew', Author(firstnames='Raquel', Author(firstnames='Rella', Author(firstnames='Rose F', Author(firstnames='Rosemary', Author(firstnames='Rukhsana', Author(firstnames='Sarah H', Author(firstnames='Sergi', Author(firstnames='Sonia M', Author(firstnames='Sonia', Author(firstnames='Stephanie K', Author(firstnames='Stephen J', Author(firstnames='Stephen R', Author(firstnames='Steve M', Author(firstnames='Susana', Author(firstnames='Swati', Author(firstnames='Ulla', Author(firstnames='Umberto', Author(firstnames='Valerie', Author(firstnames='Vera', Author(firstnames='Xavier', Author(firstnames='Yue', CollabAuthor(name='Subpatent Malaria in Pregnancy Group', Falciparum* / drug therapy, Female, Humans, Kasia Stepniewska, Malaria, Malaria* / prevention \& control, MEDLINE, Meta-Analysis, National Center for Biotechnology Information, National Institutes of Health, National Library of Medicine, NCBI, NIH, NLM, Non-U.S. Gov't, P.H.S., PMC10880462, Pregnancy, Prevalence, PubMed Abstract, Research Support, Risk Factors, Systematic review, U.S. Gov't},

pubstate = {published},

tppubtype = {article}

}

@article{nokey,

title = {Associations between dental problems and underweight status among rural women in Burkina Faso: results from the first WHO Stepwise Approach to Surveillance (STEPS) survey},

author = {Jeoffray Diend\'{e}r\'{e} and Augustin Nawidimbasba Zeba and Sibraogo Kiemtor\'{e} and Olivier Ouahamin Sombi\'{e} and Philippe Fayemendy and Pierre J\'{e}sus and Athanase Millogo and Aly Savadogo and Halidou Tinto and Jean-Claude Desport},

url = {https://www.cambridge.org/core/product/identifier/S1368980021004080/type/journal_article},

doi = {10.1017/S1368980021004080},

issn = {1368-9800},

year  = {2022},

date = {2022-01-01},

journal = {Public Health Nutrition},

volume = {25},

issue = {8},

pages = {2214-2224},

abstract = {OBJECTIVE To explore the relationships between dental problems and underweight status among rural women in Burkina Faso by using nationally representative data. DESIGN This was a cross-sectional secondary study of primary data obtained by the 2013 WHO Stepwise Approach to Surveillance survey conducted in Burkina Faso. Descriptive and analytical analyses were performed using Student's t test, ANOVA, the χ2 test, Fisher's exact test and logistic regression. SETTING All thirteen Burkinab\`{e} regions were categorised using quartiles of urbanisation rates. PARTICIPANTS The participants were 1730 rural women aged 25-64 years. RESULTS The prevalence of underweight was 16·0 %, and 24·1 % of participants experienced dental problems during the 12-month period. The women with dental problems were more frequently underweight (19·9 % and 14·7 %; P \< 0·05) and had a lower mean BMI (21·1 ± 3·2 and 21·6 ± 3·7 kg/m2, P \< 0·01) than those without dental problems. More risk factors for underweight were observed in less urbanised regions among elderly individuals (\> 49 years old) and smokeless tobacco users. Age \> 49 years, professions with inconsistent income, a lack of education, smokeless tobacco use and low BMI were factors that were significantly associated with dental problems, while residency in a low-urbanisation area was a protective factor. CONCLUSION The prevalence of underweight in rural Burkinab\`{e} women is among the highest in sub-Saharan Africa, and women with dental problems are more frequently affected than those without dental problems. Public health measures for the prevention of these disorders should specifically target women aged over 49 years and smokeless tobacco users.},

keywords = {Burkina Faso, Dental problems, Prevalence, Risk Factors, Rural women, Underweight},

pubstate = {published},

tppubtype = {article}

}

@article{Ouoba2021-ug,

title = {Epidemiologic profile of hepatitis C virus infection and  genotype distribution in Burkina Faso: a systematic review with  meta-analysis},

author = {Serge Ouoba and Jean Claude Romaric Pingdwinde Ouedraogo and Moussa Lingani and Bunthen E and Md Razeen Ashraf Hussain and Ko Ko and Shintaro Nagashima and Aya Sugiyama and Tomoyuki Akita and Halidou Tinto and Junko Tanaka},

doi = {10.1186/s12879-021-06817-x},

issn = {1471-2334},

year  = {2021},

date = {2021-11-01},

urldate = {2021-11-01},

journal = {BMC Infect. Dis.},

volume = {21},

number = {1},

pages = {1126},

publisher = {Springer Science and Business Media LLC},

abstract = {BACKGROUND: Detailed characteristics of Hepatitis C virus (HCV) 

 infection in Burkina Faso are scarce. The main aim of this study 

 was to assess HCV seroprevalence in various settings and 

 populations at risk in Burkina Faso between 1990 and 2020. 

 Secondary objectives included the prevalence of HCV Ribonucleic 

 acid (RNA) and the distribution of HCV genotypes. METHODS: A 

 systematic database search, supplemented by a manual search, was 

 conducted in PubMed, Web of Science, Scopus, and African Index 

 Medicus. Studies reporting HCV seroprevalence data in low and 

 high-risk populations in Burkina Faso were included, and a 

 random-effects meta-analysis was applied. Risk of bias was 

 assessed using the Joanna Briggs institute checklist. RESULTS: 

 Low-risk populations were examined in 31 studies involving a 

 total of 168,151 subjects, of whom 8330 were positive for HCV 

 antibodies. Six studies included a total of 1484 high-risk 

 persons, and 96 had antibodies to HCV. The pooled seroprevalence 

 in low-risk populations was 3.72% (95% CI: 3.20-4.28) and 

 4.75% (95% CI: 1.79-8.94) in high-risk groups. A 

 non-significant decreasing trend was observed over the study 

 period. Seven studies tested HCV RNA in a total of 4759 

 individuals at low risk for HCV infection, and 81 were positive. 

 The meta-analysis of HCV RNA yielded a pooled prevalence of 

 1.65% (95% CI: 0.74-2.89%) in low-risk populations, which is 

 assumed to be indicative of HCV prevalence in the general 

 population of Burkina Faso and suggests that about 301,174 

 people are active HCV carriers in the country. Genotypes 2 and 1 

 were the most frequent, with 60.3% and 25.0%, respectively. 

 CONCLUSIONS: HCV seroprevalence is intermediate in Burkina Faso 

 and indicates the need to implement effective control 

 strategies. There is a paucity of data at the national level and 

 for rural and high-risk populations. General population 

 screening and linkage to care are recommended, with special 

 attention to rural and high-risk populations.},

note = {© 2021. The Author(s).

PMID: 34724902 

PMCID: PMC8561994},

keywords = {Burkina Faso, Burkina Faso/epidemiology, Genotype, Hepacivirus/genetics, Hepatitis C, Hepatitis C/epidemiology, Humans, Prevalence, Seroepidemiologic Studies, Seroprevalence, Systematic review},

pubstate = {published},

tppubtype = {article}

}

@article{Diendere2021-lc,

title = {Associations between dental problems and underweight status  among rural women in Burkina Faso: results from the first WHO  Stepwise Approach to Surveillance (STEPS) survey},

author = {Jeoffray Diend\'{e}r\'{e} and Augustin Nawidimbasba Zeba and Sibraogo Kiemtor\'{e} and Olivier Ouahamin Sombi\'{e} and Philippe Fayemendy and Pierre J\'{e}sus and Athanase Millogo and Aly Savadogo and Halidou Tinto and Jean-Claude Desport},

doi = {10.1017/S1368980021004080},

issn = {1475-2727 1368-9800},

year  = {2021},

date = {2021-10-07},

urldate = {2021-10-07},

journal = {Public Health Nutr.},

pages = {1--11},

publisher = {Cambridge University Press (CUP)},

abstract = {OBJECTIVE: To explore the relationships between dental problems 

 and underweight status among rural women in Burkina Faso by 

 using nationally representative data. DESIGN: This was a 

 cross-sectional secondary study of primary data obtained by the 

 2013 WHO Stepwise Approach to Surveillance survey conducted in 

 Burkina Faso. Descriptive and analytical analyses were performed 

 using Student's t test, ANOVA, the $chi$2 test, Fisher's exact 

 test and logistic regression. SETTING: All thirteen 

 Burkinab`e regions were categorised using quartiles of 

 urbanisation rates. PARTICIPANTS: The participants were 1730 

 rural women aged 25-64 years. RESULTS: The prevalence of 

 underweight was 16·0 %, and 24·1 % of participants experienced 

 dental problems during the 12-month period. The women with 

 dental problems were more frequently underweight (19·9 % and 

 14·7 %; P 49 years old) and smokeless tobacco users. Age \> 49 

 years, professions with inconsistent income, a lack of 

 education, smokeless tobacco use and low BMI were factors that 

 were significantly associated with dental problems, while 

 residency in a low-urbanisation area was a protective factor. 

 CONCLUSION: The prevalence of underweight in rural Burkinab`e 

 women is among the highest in sub-Saharan Africa, and women with 

 dental problems are more frequently affected than those without 

 dental problems. Public health measures for the prevention of 

 these disorders should specifically target women aged over 49 

 years and smokeless tobacco users.},

note = {Place: England

PMID: 34615560},

keywords = {Burkina Faso, Dental problems, Prevalence, Risk Factors, Rural women, Underweight},

pubstate = {published},

tppubtype = {article}

}

@article{Rouamba2021-gn,

title = {Asymptomatic malaria and anaemia among pregnant women during  high and low malaria transmission seasons in Burkina Faso:  household-based cross-sectional surveys in Burkina Faso, 2013  and 2017},

author = {Toussaint Rouamba and S\'{e}kou Samadoulougou and Mady Ou\'{e}draogo and Herv\'{e} Hien and Halidou Tinto and Fati Kirakoya-Samadoulougou},

doi = {10.1186/s12936-021-03703-4},

issn = {1475-2875},

year  = {2021},

date = {2021-05-01},

urldate = {2021-05-01},

journal = {Malar. J.},

volume = {20},

number = {1},

pages = {211},

publisher = {Springer Science and Business Media LLC},

abstract = {BACKGROUND: Malaria in endemic countries is often asymptomatic 

 during pregnancy, but it has substantial consequences for both 

 the mother and her unborn baby. During pregnancy, anaemia is an 

 important consequence of malaria infection. In Burkina Faso, the 

 intensity of malaria varies according to the season, albeit the 

 prevalence of malaria and anaemia as well as their risk factors, 

 during high and low malaria transmission seasons is 

 underexplored at the household level. METHODS: Data of 1751 

 pregnant women from October 2013 to March 2014 and 1931 pregnant 

 women from April 2017 to June 2017 were drawn from two 

 cross-sectional household surveys conducted in 24 health 

 districts of Burkina Faso. Pregnant women were tested for 

 malaria in their household after consenting. Asymptomatic 

 carriage was defined as a positive result from malaria rapid 

 diagnostic tests in the absence of clinical symptoms of malaria. 

 Anaemia was defined as haemoglobin level less than 11 g/dL in 

 the first and third trimester and less than 10.5 g/dL in the 

 second trimester of pregnancy. RESULTS: Prevalence of 

 asymptomatic malaria in pregnancy was estimated at 23.9% (95% 

 CI 20.2-28.0) during the high transmission season 

 (October-November) in 2013. During the low transmission season, 

 it was 12.7% (95% CI 10.9-14.7) between December and March in 

 2013-2014 and halved (6.4%; 95% CI 5.3-7.6) between April and 

 June 2017. Anaemia prevalence was estimated at 59.4% (95% CI 

 54.8-63.8) during the high transmission season in 2013. During 

 the low transmission season, it was 50.6% (95% CI 47.7-53.4) 

 between December and March 2013-2014 and 65.0% (95% CI 

 62.8-67.2) between April and June, 2017. CONCLUSION: This study 

 revealed that the prevalence of malaria asymptomatic carriage 

 and anaemia among pregnant women at the community level remain 

 high throughout the year. Thus, more efforts are needed to 

 increase prevention measures such as IPTp-SP coverage in order 

 to reduce anaemia and contribute to preventing low birth weight 

 and poor pregnancy outcomes.},

keywords = {Adult, Anemia/epidemiology/parasitology, Asymptomatic carriage, Asymptomatic Infections/epidemiology, Burkina Faso/epidemiology, Community, Cross-Sectional Studies, Female, Haemoglobin, Humans, Malaria/epidemiology/parasitology, Parasitic/epidemiology/parasitology, Plasmodium, Pregnancy, Pregnancy Complications, Pregnant, Pregnant Women, Prevalence, Young Adult},

pubstate = {published},

tppubtype = {article}

}

@article{Lompo2021-sk,

title = {Pathogens associated with acute diarrhea, and comorbidity with  malaria among children under five years old in rural Burkina  Faso},

author = {Palpouguini Lompo and Marc Christian Tahita and Hermann Sorgho and William Kabor\'{e} and Adama Kazienga and Ashmed Cheick Bachirou Nana and Hamtandi Magloire Natama and Isidore Juste Ouindgueta Bonkoungou and Nicolas Barro and Halidou Tinto},

doi = {10.11604/pamj.2021.38.259.15864},

issn = {1937-8688},

year  = {2021},

date = {2021-03-01},

urldate = {2021-03-01},

journal = {Pan Afr. Med. J.},

volume = {38},

pages = {259},

publisher = {Pan African Medical Journal},

abstract = {INTRODUCTION: acute diarrhea in children under five years is a public health problem in developing countries and particularly in malaria-endemic areas where both  diseases co-exist. The present study examined the etiology of childhood diarrhea and  its comorbidity with malaria in a rural area of Burkina Faso. 

METHODS: conventional  culture techniques, direct stools examination, and viruses´ detection by rapid tests  were performed on the fresh stools and microscopy was used to diagnose malaria. Some  risk factors were also assessed. RESULTS: on a total of 191 samples collected, at  least one pathogen was identified in 89 cases (46.6%). The proportions of pathogens  found on the 89 positive stool samples were parasites 51.69% (46 cases), viruses  39.33% (35 cases), and bacteria 14.61% (13 cases), respectively. The relationship  between malaria and infectious diarrhea was significant in viral and parasites  causes (p=0.005 and 0.043 respectively). Fever, vomiting and abdominal pain were the  major symptoms associated with diarrhea, with 71.51%, 31.72% and 23.66%  respectively. The highest viral diarrhea prevalence was reported during the dry  season (OR=5.29, 95% CI: 1.74 - 16.07, p=0.001) while parasite diarrhea was more  encountered during the rainy season (OR=0.41, 95% CI: 0.33 - 0.87, p=0.011).  CONCLUSION: Giardia spp and rotavirus were the leading cause of acute diarrhea in  Nanoro, Burkina Faso with a predominance of rotavirus in children less than 2 years.  Parasite and viral diarrhea were the most pathogens associated with malaria.  However, the high rate of negative stool samples suggests the need to determine  other enteric microorganisms.},

note = {Copyright: Palpouguini Lompo et al.

PMID: 34104307 

PMCID: PMC8164431},

keywords = {Abdominal Pain/epidemiology, Acute Disease, bacteria, Burkina Faso, Burkina Faso/epidemiology, Child, Comorbidity, Diarrhea, Diarrhea/epidemiology/microbiology, Female, Fever/epidemiology, Giardiasis/epidemiology, Humans, Infant, infectious, Malaria, Malaria/epidemiology, Male, parasite, pathogens, Preschool, Prevalence, Risk Factors, rotavirus, Rotavirus Infections/epidemiology, Rural Population, Seasons, Vomiting/epidemiology},

pubstate = {published},

tppubtype = {article}

}