| Yacouba Sawadogo, Lokman Galal, Essia Belarbi, Arsène Zongo, Grit Schubert, Fabian Leendertz, Abdoulie Kanteh, Abdul Karim Sesay, Annette Erhart, Anne-Laure Bañuls, Zékiba Tarnagda, Sylvain Godreuil, Halidou Tinto, Abdoul-Salam Ouedraogo Genomic Epidemiology of SARS-CoV-2 in Western Burkina Faso, West Africa (Journal Article) In: Viruses, vol. 14, iss. 12, pp. 2788, 2022, ISSN: 1999-4915. @article{Sawadogo2022,
title = {Genomic Epidemiology of SARS-CoV-2 in Western Burkina Faso, West Africa},
author = {Yacouba Sawadogo and Lokman Galal and Essia Belarbi and Ars\`{e}ne Zongo and Grit Schubert and Fabian Leendertz and Abdoulie Kanteh and Abdul Karim Sesay and Annette Erhart and Anne-Laure Ba\~{n}uls and Z\'{e}kiba Tarnagda and Sylvain Godreuil and Halidou Tinto and Abdoul-Salam Ouedraogo},
url = {https://www.mdpi.com/1999-4915/14/12/2788},
doi = {10.3390/v14122788},
issn = {1999-4915},
year = {2022},
date = {2022-01-01},
journal = {Viruses},
volume = {14},
issue = {12},
pages = {2788},
abstract = {\<p\>Background: After its initial detection in Wuhan, China, in December 2019, SARS-CoV-2 has spread rapidly, causing successive epidemic waves worldwide. This study aims to provide a genomic epidemiology of SARS-CoV-2 in Burkina Faso. Methods: Three hundred and seventy-seven SARS-CoV-2 genomes obtained from PCR-positive nasopharyngeal samples (PCR cycle threshold score \< 35) collected between 5 May 2020, and 31 January 2022 were analyzed. Genomic sequences were assigned to phylogenetic clades using NextClade and to Pango lineages using pangolin. Phylogenetic and phylogeographic analyses were performed to determine the geographical sources and time of virus introduction in Burkina Faso. Results: The analyzed SARS-CoV-2 genomes can be assigned to 10 phylogenetic clades and 27 Pango lineages already described worldwide. Our analyses revealed the important role of cross-border human mobility in the successive SARS-CoV-2 introductions in Burkina Faso from neighboring countries. Conclusions: This study provides additional insights into the genomic epidemiology of SARS-CoV-2 in West Africa. It highlights the importance of land travel in the spread of the virus and the need to rapidly implement preventive policies. Regional cross-border collaborations and the adherence of the general population to government policies are key to prevent new epidemic waves.\</p\>},
keywords = {Burkina Faso, COVID-19, genomic epidemiology, SARS-Cov-2, West Africa, Whole Genome Sequencing},
pubstate = {published},
tppubtype = {article}
}
<p>Background: After its initial detection in Wuhan, China, in December 2019, SARS-CoV-2 has spread rapidly, causing successive epidemic waves worldwide. This study aims to provide a genomic epidemiology of SARS-CoV-2 in Burkina Faso. Methods: Three hundred and seventy-seven SARS-CoV-2 genomes obtained from PCR-positive nasopharyngeal samples (PCR cycle threshold score < 35) collected between 5 May 2020, and 31 January 2022 were analyzed. Genomic sequences were assigned to phylogenetic clades using NextClade and to Pango lineages using pangolin. Phylogenetic and phylogeographic analyses were performed to determine the geographical sources and time of virus introduction in Burkina Faso. Results: The analyzed SARS-CoV-2 genomes can be assigned to 10 phylogenetic clades and 27 Pango lineages already described worldwide. Our analyses revealed the important role of cross-border human mobility in the successive SARS-CoV-2 introductions in Burkina Faso from neighboring countries. Conclusions: This study provides additional insights into the genomic epidemiology of SARS-CoV-2 in West Africa. It highlights the importance of land travel in the spread of the virus and the need to rapidly implement preventive policies. Regional cross-border collaborations and the adherence of the general population to government policies are key to prevent new epidemic waves.</p> |
