2022
|
Journal Articles
|
 | Biébo Bihoun, Serge Henri Zango, Maminata Traoré-Coulibaly, Innocent Valea, Raffaella Ravinetto, Jean Pierre Van Geertruyden, Umberto D’Alessandro, Halidou Tinto, Annie Robert Age-modified factors associated with placental malaria in rural Burkina Faso. (Journal Article) In: BMC pregnancy and childbirth, vol. 22, iss. 1, pp. 248, 2022, ISSN: 1471-2393. @article{nokey,
title = {Age-modified factors associated with placental malaria in rural Burkina Faso.},
author = {Bi\'{e}bo Bihoun and Serge Henri Zango and Maminata Traor\'{e}-Coulibaly and Innocent Valea and Raffaella Ravinetto and Jean Pierre Van Geertruyden and Umberto D'Alessandro and Halidou Tinto and Annie Robert},
doi = {10.1186/s12884-022-04568-4},
issn = {1471-2393},
year = {2022},
date = {2022-03-01},
urldate = {2022-03-01},
journal = {BMC pregnancy and childbirth},
volume = {22},
issue = {1},
pages = {248},
abstract = {BACKGROUND: Malaria in pregnancy can result in placental infection with fetal implications. This study aimed at assessing placental malaria (PM) prevalence and its associated factors in a cohort of pregnant women with peripheral malaria and their offspring. METHOD: The data were collected in the framework of a clinical trial on treatments for malaria in pregnant women . Placental malaria (PM) was diagnosed by histopathological detection of parasites and/or malaria pigment on placenta biopsies taken at delivery. Factors associated with PM were assessed using logistic regression. RESULTS: Out of 745 biopsies examined, PM was diagnosed in 86.8 % of women. Acute, chronic and past PM were retrieved in 11 (1.5 %), 170 (22.8 %), and 466 (62.6 %) women, respectively. A modifying effect was observed in the association of gravidity or anemia at the study start with pooled PM (presence of parasites and/or malaria pigment). In women under 30, gravidity ≤ 2 was associated with an increased prevalence of pooled PM but in women aged 30 years or more, gravidity was no more associated with pooled PM (OR 6.81, 95 % CI 3.18 - 14.60; and OR 0.52, 95 % CI 0.10 - 2.76, respectively). Anemia was associated with pooled PM in women under 30 (OR 1.96, 95 % CI 1.03 - 3.72) but not in women aged 30 years or more (OR 0.68, 95 % CI 0.31 - 1.49). Similarly, the association of gravidity with past-chronic PM depended also on age. A higher prevalence of active PM was observed in women under 30 presenting with symptomatic malaria (OR 3.79, 95 % CI 1.55 - 9.27), while there was no significant increase in the prevalence of active PM (presence of parasites only) in women with symptomatic malaria when aged 30 years or more (OR 0.42, 95 % CI 0.10 - 1.75). In women with chronic PM, the prevalence of low birth weight or prematurity was the highest (31.2 %) as compared with past PM or no PM. CONCLUSION: Despite the rapid diagnosis and efficacious treatment of peripheral infection, the prevalence of placental malaria remained high in women with P. falciparum peripheral infection in Nanoro, especially in younger women This underlines the importance of preventive measures in this specific group.},
keywords = {*Malaria, *Malaria/epidemiology, Adult, Burkina Faso, Burkina Faso/epidemiology, Falciparum/parasitology, Female, Gravidity, Humans, Malaria, placenta, Placenta/parasitology, Pregnancy, Risk Factors},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Malaria in pregnancy can result in placental infection with fetal implications. This study aimed at assessing placental malaria (PM) prevalence and its associated factors in a cohort of pregnant women with peripheral malaria and their offspring. METHOD: The data were collected in the framework of a clinical trial on treatments for malaria in pregnant women . Placental malaria (PM) was diagnosed by histopathological detection of parasites and/or malaria pigment on placenta biopsies taken at delivery. Factors associated with PM were assessed using logistic regression. RESULTS: Out of 745 biopsies examined, PM was diagnosed in 86.8 % of women. Acute, chronic and past PM were retrieved in 11 (1.5 %), 170 (22.8 %), and 466 (62.6 %) women, respectively. A modifying effect was observed in the association of gravidity or anemia at the study start with pooled PM (presence of parasites and/or malaria pigment). In women under 30, gravidity ≤ 2 was associated with an increased prevalence of pooled PM but in women aged 30 years or more, gravidity was no more associated with pooled PM (OR 6.81, 95 % CI 3.18 – 14.60; and OR 0.52, 95 % CI 0.10 – 2.76, respectively). Anemia was associated with pooled PM in women under 30 (OR 1.96, 95 % CI 1.03 – 3.72) but not in women aged 30 years or more (OR 0.68, 95 % CI 0.31 – 1.49). Similarly, the association of gravidity with past-chronic PM depended also on age. A higher prevalence of active PM was observed in women under 30 presenting with symptomatic malaria (OR 3.79, 95 % CI 1.55 – 9.27), while there was no significant increase in the prevalence of active PM (presence of parasites only) in women with symptomatic malaria when aged 30 years or more (OR 0.42, 95 % CI 0.10 – 1.75). In women with chronic PM, the prevalence of low birth weight or prematurity was the highest (31.2 %) as compared with past PM or no PM. CONCLUSION: Despite the rapid diagnosis and efficacious treatment of peripheral infection, the prevalence of placental malaria remained high in women with P. falciparum peripheral infection in Nanoro, especially in younger women This underlines the importance of preventive measures in this specific group. |
 | Moussa Lingani, Serge Henri Zango, Innocent Valéa, Georges Somé, Maïmouna Sanou, Sékou O. Samadoulougou, Serge Ouoba, Eli Rouamba, Annie Robert, Michèle Dramaix, Philippe Donnen, Halidou Tinto Low birth weight and its associated risk factors in a rural health district of Burkina Faso: a cross sectional study. (Journal Article) In: BMC pregnancy and childbirth, vol. 22, iss. 1, pp. 228, 2022, ISSN: 1471-2393. @article{nokey,
title = {Low birth weight and its associated risk factors in a rural health district of Burkina Faso: a cross sectional study.},
author = {Moussa Lingani and Serge Henri Zango and Innocent Val\'{e}a and Georges Som\'{e} and Ma\"{i}mouna Sanou and S\'{e}kou O. Samadoulougou and Serge Ouoba and Eli Rouamba and Annie Robert and Mich\`{e}le Dramaix and Philippe Donnen and Halidou Tinto},
doi = {10.1186/s12884-022-04554-w},
issn = {1471-2393},
year = {2022},
date = {2022-03-01},
urldate = {2022-03-01},
journal = {BMC pregnancy and childbirth},
volume = {22},
issue = {1},
pages = {228},
abstract = {BACKGROUND: Low birth weight (LBW) is a major factor of neonate mortality that particularly affects developing countries. However, the scarcity of data to support decision making to reduce LBW occurrence is a major obstacle in sub-Saharan Africa. The aim of this research was to determine the prevalence and associated factors of LBW at the Yako health district in a rural area of Burkina Faso. METHODS: A cross sectional survey was conducted at four peripheral health centers among mothers and their newly delivered babies. The mothers' socio-demographic and obstetrical characteristics were collected by face-to-face interview or by review of antenatal care books. Maternal malaria was tested by standard microscopy and neonates' birth weights were documented. Multivariate logistic regression was used to determine factors associated with LBW. A p-value < 0.05 was considered statistically significant. RESULTS: Of 600 neonates examined, the prevalence of low birth weight was 11.0%. Adjustment for socio-demographic characteristic, medical conditions, obstetrical history, malaria prevention measures by multivariate logistic regression found that being a primigravid mother (aOR = 1.8, [95% CI: 1.1-3.0]), the presence of malaria infection (aOR = 1.9, [95% CI: 1.1-3.5]), the uptake of less than three doses of sulfadoxine-pyrimethamine for the intermittent preventive treatment of malaria in pregnancy (IPTp-SP) (aOR = 2.2, [95% CI: 1.3-3.9]), the presence of maternal fever at the time of delivery (aOR = 2.8, [95% CI: 1.5-5.3]) and being a female neonate (aOR = 1.9, [95% CI: 1.1-3.3]) were independently associated with an increased risk of LBW occurrence. The number of antenatal visits performed by the mother during her pregnancy did not provide any direct protection for low birth weight. CONCLUSION: The prevalence of LBW remained high in the study area. Maternal malaria, fever and low uptake of sulfadoxine-pyrimethamine doses were significantly associated with LBW and should be adequately addressed by public health interventions.},
keywords = {*Antimalarials/therapeutic use, *Rural Health, Associated factors, Burkina Faso, Burkina Faso/epidemiology, Cross-Sectional Studies, Female, Humans, Infant, Low Birth Weight, Newborn, Pregnancy, Risk Factors, Rural area},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Low birth weight (LBW) is a major factor of neonate mortality that particularly affects developing countries. However, the scarcity of data to support decision making to reduce LBW occurrence is a major obstacle in sub-Saharan Africa. The aim of this research was to determine the prevalence and associated factors of LBW at the Yako health district in a rural area of Burkina Faso. METHODS: A cross sectional survey was conducted at four peripheral health centers among mothers and their newly delivered babies. The mothers’ socio-demographic and obstetrical characteristics were collected by face-to-face interview or by review of antenatal care books. Maternal malaria was tested by standard microscopy and neonates’ birth weights were documented. Multivariate logistic regression was used to determine factors associated with LBW. A p-value < 0.05 was considered statistically significant. RESULTS: Of 600 neonates examined, the prevalence of low birth weight was 11.0%. Adjustment for socio-demographic characteristic, medical conditions, obstetrical history, malaria prevention measures by multivariate logistic regression found that being a primigravid mother (aOR = 1.8, [95% CI: 1.1-3.0]), the presence of malaria infection (aOR = 1.9, [95% CI: 1.1-3.5]), the uptake of less than three doses of sulfadoxine-pyrimethamine for the intermittent preventive treatment of malaria in pregnancy (IPTp-SP) (aOR = 2.2, [95% CI: 1.3-3.9]), the presence of maternal fever at the time of delivery (aOR = 2.8, [95% CI: 1.5-5.3]) and being a female neonate (aOR = 1.9, [95% CI: 1.1-3.3]) were independently associated with an increased risk of LBW occurrence. The number of antenatal visits performed by the mother during her pregnancy did not provide any direct protection for low birth weight. CONCLUSION: The prevalence of LBW remained high in the study area. Maternal malaria, fever and low uptake of sulfadoxine-pyrimethamine doses were significantly associated with LBW and should be adequately addressed by public health interventions. |
| Jeoffray Diendéré, Augustin Nawidimbasba Zeba, Sibraogo Kiemtoré, Olivier Ouahamin Sombié, Philippe Fayemendy, Pierre Jésus, Athanase Millogo, Aly Savadogo, Halidou Tinto, Jean-Claude Desport Associations between dental problems and underweight status among rural women in Burkina Faso: results from the first WHO Stepwise Approach to Surveillance (STEPS) survey (Journal Article) In: Public Health Nutrition, vol. 25, iss. 8, pp. 2214-2224, 2022, ISSN: 1368-9800. @article{nokey,
title = {Associations between dental problems and underweight status among rural women in Burkina Faso: results from the first WHO Stepwise Approach to Surveillance (STEPS) survey},
author = {Jeoffray Diend\'{e}r\'{e} and Augustin Nawidimbasba Zeba and Sibraogo Kiemtor\'{e} and Olivier Ouahamin Sombi\'{e} and Philippe Fayemendy and Pierre J\'{e}sus and Athanase Millogo and Aly Savadogo and Halidou Tinto and Jean-Claude Desport},
url = {https://www.cambridge.org/core/product/identifier/S1368980021004080/type/journal_article},
doi = {10.1017/S1368980021004080},
issn = {1368-9800},
year = {2022},
date = {2022-01-01},
journal = {Public Health Nutrition},
volume = {25},
issue = {8},
pages = {2214-2224},
abstract = {OBJECTIVE To explore the relationships between dental problems and underweight status among rural women in Burkina Faso by using nationally representative data. DESIGN This was a cross-sectional secondary study of primary data obtained by the 2013 WHO Stepwise Approach to Surveillance survey conducted in Burkina Faso. Descriptive and analytical analyses were performed using Student's t test, ANOVA, the χ2 test, Fisher's exact test and logistic regression. SETTING All thirteen Burkinab\`{e} regions were categorised using quartiles of urbanisation rates. PARTICIPANTS The participants were 1730 rural women aged 25-64 years. RESULTS The prevalence of underweight was 16·0 %, and 24·1 % of participants experienced dental problems during the 12-month period. The women with dental problems were more frequently underweight (19·9 % and 14·7 %; P < 0·05) and had a lower mean BMI (21·1 ± 3·2 and 21·6 ± 3·7 kg/m2, P < 0·01) than those without dental problems. More risk factors for underweight were observed in less urbanised regions among elderly individuals (> 49 years old) and smokeless tobacco users. Age > 49 years, professions with inconsistent income, a lack of education, smokeless tobacco use and low BMI were factors that were significantly associated with dental problems, while residency in a low-urbanisation area was a protective factor. CONCLUSION The prevalence of underweight in rural Burkinab\`{e} women is among the highest in sub-Saharan Africa, and women with dental problems are more frequently affected than those without dental problems. Public health measures for the prevention of these disorders should specifically target women aged over 49 years and smokeless tobacco users.},
keywords = {Burkina Faso, Dental problems, Prevalence, Risk Factors, Rural women, Underweight},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVE To explore the relationships between dental problems and underweight status among rural women in Burkina Faso by using nationally representative data. DESIGN This was a cross-sectional secondary study of primary data obtained by the 2013 WHO Stepwise Approach to Surveillance survey conducted in Burkina Faso. Descriptive and analytical analyses were performed using Student’s t test, ANOVA, the χ2 test, Fisher’s exact test and logistic regression. SETTING All thirteen Burkinabè regions were categorised using quartiles of urbanisation rates. PARTICIPANTS The participants were 1730 rural women aged 25-64 years. RESULTS The prevalence of underweight was 16·0 %, and 24·1 % of participants experienced dental problems during the 12-month period. The women with dental problems were more frequently underweight (19·9 % and 14·7 %; P < 0·05) and had a lower mean BMI (21·1 ± 3·2 and 21·6 ± 3·7 kg/m2, P < 0·01) than those without dental problems. More risk factors for underweight were observed in less urbanised regions among elderly individuals (> 49 years old) and smokeless tobacco users. Age > 49 years, professions with inconsistent income, a lack of education, smokeless tobacco use and low BMI were factors that were significantly associated with dental problems, while residency in a low-urbanisation area was a protective factor. CONCLUSION The prevalence of underweight in rural Burkinabè women is among the highest in sub-Saharan Africa, and women with dental problems are more frequently affected than those without dental problems. Public health measures for the prevention of these disorders should specifically target women aged over 49 years and smokeless tobacco users. |
2021
|
Journal Articles
|
 | Jeoffray Diendéré, Augustin Nawidimbasba Zeba, Sibraogo Kiemtoré, Olivier Ouahamin Sombié, Philippe Fayemendy, Pierre Jésus, Athanase Millogo, Aly Savadogo, Halidou Tinto, Jean-Claude Desport Associations between dental problems and underweight status among rural women in Burkina Faso: results from the first WHO Stepwise Approach to Surveillance (STEPS) survey (Journal Article) In: Public Health Nutr., pp. 1–11, 2021, ISSN: 1475-2727 1368-9800, (Place: England
PMID: 34615560). @article{Diendere2021-lc,
title = {Associations between dental problems and underweight status among rural women in Burkina Faso: results from the first WHO Stepwise Approach to Surveillance (STEPS) survey},
author = {Jeoffray Diend\'{e}r\'{e} and Augustin Nawidimbasba Zeba and Sibraogo Kiemtor\'{e} and Olivier Ouahamin Sombi\'{e} and Philippe Fayemendy and Pierre J\'{e}sus and Athanase Millogo and Aly Savadogo and Halidou Tinto and Jean-Claude Desport},
doi = {10.1017/S1368980021004080},
issn = {1475-2727 1368-9800},
year = {2021},
date = {2021-10-07},
urldate = {2021-10-07},
journal = {Public Health Nutr.},
pages = {1--11},
publisher = {Cambridge University Press (CUP)},
abstract = {OBJECTIVE: To explore the relationships between dental problems
and underweight status among rural women in Burkina Faso by
using nationally representative data. DESIGN: This was a
cross-sectional secondary study of primary data obtained by the
2013 WHO Stepwise Approach to Surveillance survey conducted in
Burkina Faso. Descriptive and analytical analyses were performed
using Student's t test, ANOVA, the $chi$2 test, Fisher's exact
test and logistic regression. SETTING: All thirteen
Burkinab`e regions were categorised using quartiles of
urbanisation rates. PARTICIPANTS: The participants were 1730
rural women aged 25-64 years. RESULTS: The prevalence of
underweight was 16·0 %, and 24·1 % of participants experienced
dental problems during the 12-month period. The women with
dental problems were more frequently underweight (19·9 % and
14·7 %; P 49 years old) and smokeless tobacco users. Age > 49
years, professions with inconsistent income, a lack of
education, smokeless tobacco use and low BMI were factors that
were significantly associated with dental problems, while
residency in a low-urbanisation area was a protective factor.
CONCLUSION: The prevalence of underweight in rural Burkinab`e
women is among the highest in sub-Saharan Africa, and women with
dental problems are more frequently affected than those without
dental problems. Public health measures for the prevention of
these disorders should specifically target women aged over 49
years and smokeless tobacco users.},
note = {Place: England
PMID: 34615560},
keywords = {Burkina Faso, Dental problems, Prevalence, Risk Factors, Rural women, Underweight},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVE: To explore the relationships between dental problems
and underweight status among rural women in Burkina Faso by
using nationally representative data. DESIGN: This was a
cross-sectional secondary study of primary data obtained by the
2013 WHO Stepwise Approach to Surveillance survey conducted in
Burkina Faso. Descriptive and analytical analyses were performed
using Student’s t test, ANOVA, the $chi$2 test, Fisher’s exact
test and logistic regression. SETTING: All thirteen
Burkinab`e regions were categorised using quartiles of
urbanisation rates. PARTICIPANTS: The participants were 1730
rural women aged 25-64 years. RESULTS: The prevalence of
underweight was 16·0 %, and 24·1 % of participants experienced
dental problems during the 12-month period. The women with
dental problems were more frequently underweight (19·9 % and
14·7 %; P 49 years old) and smokeless tobacco users. Age > 49
years, professions with inconsistent income, a lack of
education, smokeless tobacco use and low BMI were factors that
were significantly associated with dental problems, while
residency in a low-urbanisation area was a protective factor.
CONCLUSION: The prevalence of underweight in rural Burkinab`e
women is among the highest in sub-Saharan Africa, and women with
dental problems are more frequently affected than those without
dental problems. Public health measures for the prevention of
these disorders should specifically target women aged over 49
years and smokeless tobacco users. |
 | Engelbert A Nonterah, Michiel L Bots, Abraham Oduro, Godfred Agongo, Cassandra C Soo, Lisa K Micklesfield, Felistas Mashinya, Palwendé R Boua, Shukri F Mohamed, Alisha N Wade, Catherine Kyobutungi, Halidou Tinto, Shane A Norris, Stephen M Tollman, Mich`ele Ramsay, Diederick E Grobbee, Kerstin Klipstein-Grobusch, Nigel J Crowther, AWI-Gen, H3Africa Consortium Adiposity phenotypes and subclinical atherosclerosis in adults from sub-Saharan Africa: An H3Africa AWI-gen study (Journal Article) In: Glob. Heart, vol. 16, no. 1, pp. 19, 2021, ISSN: 2211-8179 2211-8160, (Copyright: © 2021 The Author(s).
PMID: 33833943
PMCID: PMC7977036). @article{Nonterah2021-pc,
title = {Adiposity phenotypes and subclinical atherosclerosis in adults from sub-Saharan Africa: An H3Africa AWI-gen study},
author = {Engelbert A Nonterah and Michiel L Bots and Abraham Oduro and Godfred Agongo and Cassandra C Soo and Lisa K Micklesfield and Felistas Mashinya and Palwend\'{e} R Boua and Shukri F Mohamed and Alisha N Wade and Catherine Kyobutungi and Halidou Tinto and Shane A Norris and Stephen M Tollman and Mich`ele Ramsay and Diederick E Grobbee and Kerstin Klipstein-Grobusch and Nigel J Crowther and AWI-Gen and H3Africa Consortium},
doi = {10.5334/gh.863},
issn = {2211-8179 2211-8160},
year = {2021},
date = {2021-03-19},
urldate = {2021-03-19},
journal = {Glob. Heart},
volume = {16},
number = {1},
pages = {19},
publisher = {Ubiquity Press, Ltd.},
abstract = {Background: Obesity and adipose tissue distribution contribute
to an increased risk of cardiovascular disease (CVD) by
promoting atherosclerosis. This association has been poorly
studied in sub-Saharan Africa (SSA) despite the rising
prevalence of cardiovascular disease. Objectives: We determined
the association between various adiposity phenotypes and carotid
intima-media thickness (CIMT), a proxy of subclinical
atherosclerosis, in a large SSA population. Methods: A
population-based cross-sectional study was performed from
2013-2016 in Burkina Faso, Ghana, Kenya and South Africa. Body
mass index (BMI), waist (WC), hip circumferences (HC), visceral
(VAT) and subcutaneous adipose tissue (SCAT) using B-mode
ultrasound were measured. Ultrasonography of left and right far
wall CIMT of the common carotid artery was used as an indicator
of subclinical atherosclerosis. Individual participant data
meta-analyses were used to determine the associations between
adiposity phenotypes and CIMT in the pooled sample while
adjusted multivariable linear regression analyses were used for
site specific analyses. Results: Data were obtained from 9,010
adults (50.3% women and a mean age of 50$pm$ 6years). Men had
higher levels of visceral fat than women while women had higher
BMI, waist and hip circumference and subcutaneous fat than men
at all sites except Burkina Faso. In the pooled analyses, BMI
($beta$-value [95% CIs]: 19.5 [16.8, 22.3] $mu$m) showed the
strongest relationship with CIMT followed by VAT (5.86 [4.65,
7.07] $mu$m), SCAT (5.00 [2.85, 7.15] $mu$m), WC (1.27 [1.09,
1.44] $mu$m) and HC (1.23 [1.04, 1.42] $mu$m). Stronger
associations were observed in men than in women. Conclusion:
Obesity within SSA will likely result in higher levels of
atherosclerosis and promote the occurrence of cardio- and
cerebrovascular events, especially in males, unless addressed
through primary prevention of obesity in both rural and urban
communities across Africa. The inverse association of VAT with
CIMT in Burkina Faso and Ghana requires further investigation.
Highlights: All adiposity phenotypes were positively associated
with common carotid intima-media thickness (CIMT) in the entire
cohort (pooled analyses).BMI had the strongest association with
CIMT compared to other phenotypes.The magnitude of association
between adiposity phenotypes and CIMT was higher in men than in
women.Subcutaneous adipose tissue was inversely associated with
CIMT only in women.An unexpected finding was the inverse
association of visceral adipose tissue with CIMT in Burkina Faso
and Ghana.},
note = {Copyright: © 2021 The Author(s).
PMID: 33833943
PMCID: PMC7977036},
keywords = {adiposity, Adult, Body Mass Index, cardiovascular disease, Carotid intima-media thickness, Cross-Sectional Studies, Female, Ghana, Humans, Male, Middle Aged, obesity, Obesity/complications/epidemiology, Phenotype, Risk Factors, sub-Saharan Africa, subclinical atherosclerosis},
pubstate = {published},
tppubtype = {article}
}
Background: Obesity and adipose tissue distribution contribute
to an increased risk of cardiovascular disease (CVD) by
promoting atherosclerosis. This association has been poorly
studied in sub-Saharan Africa (SSA) despite the rising
prevalence of cardiovascular disease. Objectives: We determined
the association between various adiposity phenotypes and carotid
intima-media thickness (CIMT), a proxy of subclinical
atherosclerosis, in a large SSA population. Methods: A
population-based cross-sectional study was performed from
2013-2016 in Burkina Faso, Ghana, Kenya and South Africa. Body
mass index (BMI), waist (WC), hip circumferences (HC), visceral
(VAT) and subcutaneous adipose tissue (SCAT) using B-mode
ultrasound were measured. Ultrasonography of left and right far
wall CIMT of the common carotid artery was used as an indicator
of subclinical atherosclerosis. Individual participant data
meta-analyses were used to determine the associations between
adiposity phenotypes and CIMT in the pooled sample while
adjusted multivariable linear regression analyses were used for
site specific analyses. Results: Data were obtained from 9,010
adults (50.3% women and a mean age of 50$pm$ 6years). Men had
higher levels of visceral fat than women while women had higher
BMI, waist and hip circumference and subcutaneous fat than men
at all sites except Burkina Faso. In the pooled analyses, BMI
($beta$-value [95% CIs]: 19.5 [16.8, 22.3] $mu$m) showed the
strongest relationship with CIMT followed by VAT (5.86 [4.65,
7.07] $mu$m), SCAT (5.00 [2.85, 7.15] $mu$m), WC (1.27 [1.09,
1.44] $mu$m) and HC (1.23 [1.04, 1.42] $mu$m). Stronger
associations were observed in men than in women. Conclusion:
Obesity within SSA will likely result in higher levels of
atherosclerosis and promote the occurrence of cardio- and
cerebrovascular events, especially in males, unless addressed
through primary prevention of obesity in both rural and urban
communities across Africa. The inverse association of VAT with
CIMT in Burkina Faso and Ghana requires further investigation.
Highlights: All adiposity phenotypes were positively associated
with common carotid intima-media thickness (CIMT) in the entire
cohort (pooled analyses).BMI had the strongest association with
CIMT compared to other phenotypes.The magnitude of association
between adiposity phenotypes and CIMT was higher in men than in
women.Subcutaneous adipose tissue was inversely associated with
CIMT only in women.An unexpected finding was the inverse
association of visceral adipose tissue with CIMT in Burkina Faso
and Ghana. |
 | Palpouguini Lompo, Marc Christian Tahita, Hermann Sorgho, William Kaboré, Adama Kazienga, Ashmed Cheick Bachirou Nana, Hamtandi Magloire Natama, Isidore Juste Ouindgueta Bonkoungou, Nicolas Barro, Halidou Tinto Pathogens associated with acute diarrhea, and comorbidity with malaria among children under five years old in rural Burkina Faso (Journal Article) In: Pan Afr. Med. J., vol. 38, pp. 259, 2021, ISSN: 1937-8688, (Copyright: Palpouguini Lompo et al.
PMID: 34104307
PMCID: PMC8164431). @article{Lompo2021-sk,
title = {Pathogens associated with acute diarrhea, and comorbidity with malaria among children under five years old in rural Burkina Faso},
author = {Palpouguini Lompo and Marc Christian Tahita and Hermann Sorgho and William Kabor\'{e} and Adama Kazienga and Ashmed Cheick Bachirou Nana and Hamtandi Magloire Natama and Isidore Juste Ouindgueta Bonkoungou and Nicolas Barro and Halidou Tinto},
doi = {10.11604/pamj.2021.38.259.15864},
issn = {1937-8688},
year = {2021},
date = {2021-03-01},
urldate = {2021-03-01},
journal = {Pan Afr. Med. J.},
volume = {38},
pages = {259},
publisher = {Pan African Medical Journal},
abstract = {INTRODUCTION: acute diarrhea in children under five years is a public health problem in developing countries and particularly in malaria-endemic areas where both diseases co-exist. The present study examined the etiology of childhood diarrhea and its comorbidity with malaria in a rural area of Burkina Faso.
METHODS: conventional culture techniques, direct stools examination, and viruses´ detection by rapid tests were performed on the fresh stools and microscopy was used to diagnose malaria. Some risk factors were also assessed. RESULTS: on a total of 191 samples collected, at least one pathogen was identified in 89 cases (46.6%). The proportions of pathogens found on the 89 positive stool samples were parasites 51.69% (46 cases), viruses 39.33% (35 cases), and bacteria 14.61% (13 cases), respectively. The relationship between malaria and infectious diarrhea was significant in viral and parasites causes (p=0.005 and 0.043 respectively). Fever, vomiting and abdominal pain were the major symptoms associated with diarrhea, with 71.51%, 31.72% and 23.66% respectively. The highest viral diarrhea prevalence was reported during the dry season (OR=5.29, 95% CI: 1.74 - 16.07, p=0.001) while parasite diarrhea was more encountered during the rainy season (OR=0.41, 95% CI: 0.33 - 0.87, p=0.011). CONCLUSION: Giardia spp and rotavirus were the leading cause of acute diarrhea in Nanoro, Burkina Faso with a predominance of rotavirus in children less than 2 years. Parasite and viral diarrhea were the most pathogens associated with malaria. However, the high rate of negative stool samples suggests the need to determine other enteric microorganisms.},
note = {Copyright: Palpouguini Lompo et al.
PMID: 34104307
PMCID: PMC8164431},
keywords = {Abdominal Pain/epidemiology, Acute Disease, bacteria, Burkina Faso, Burkina Faso/epidemiology, Child, Comorbidity, Diarrhea, Diarrhea/epidemiology/microbiology, Female, Fever/epidemiology, Giardiasis/epidemiology, Humans, Infant, infectious, Malaria, Malaria/epidemiology, Male, parasite, pathogens, Preschool, Prevalence, Risk Factors, rotavirus, Rotavirus Infections/epidemiology, Rural Population, Seasons, Vomiting/epidemiology},
pubstate = {published},
tppubtype = {article}
}
INTRODUCTION: acute diarrhea in children under five years is a public health problem in developing countries and particularly in malaria-endemic areas where both diseases co-exist. The present study examined the etiology of childhood diarrhea and its comorbidity with malaria in a rural area of Burkina Faso.
METHODS: conventional culture techniques, direct stools examination, and viruses´ detection by rapid tests were performed on the fresh stools and microscopy was used to diagnose malaria. Some risk factors were also assessed. RESULTS: on a total of 191 samples collected, at least one pathogen was identified in 89 cases (46.6%). The proportions of pathogens found on the 89 positive stool samples were parasites 51.69% (46 cases), viruses 39.33% (35 cases), and bacteria 14.61% (13 cases), respectively. The relationship between malaria and infectious diarrhea was significant in viral and parasites causes (p=0.005 and 0.043 respectively). Fever, vomiting and abdominal pain were the major symptoms associated with diarrhea, with 71.51%, 31.72% and 23.66% respectively. The highest viral diarrhea prevalence was reported during the dry season (OR=5.29, 95% CI: 1.74 – 16.07, p=0.001) while parasite diarrhea was more encountered during the rainy season (OR=0.41, 95% CI: 0.33 – 0.87, p=0.011). CONCLUSION: Giardia spp and rotavirus were the leading cause of acute diarrhea in Nanoro, Burkina Faso with a predominance of rotavirus in children less than 2 years. Parasite and viral diarrhea were the most pathogens associated with malaria. However, the high rate of negative stool samples suggests the need to determine other enteric microorganisms. |