CRUN

Ousmane Traore

Current Job Researcher
Personal Statement I am currently in “Transition” from early career researcher to an independent researcher.
Particularly focused on malaria research applied to maternal and infant health, I am also highly interested in other infectious diseases.
My MSc research allowed me to develop an operational procedure for antisera production locally for serological diagnosis of trypanosomiasis.
Although the results of this research have not been validated due to lack of funding, they provide a basis for establishing a platform that can be used to produce conjugated biomolecules: materials needed for the manufacture of immunoassays.
During my PhD training, I developed a proposal aiming to identify immunological factors that influence primiparous susceptibility to malaria during pregnancy and postpartum.
I have globally approached the (i) relationship between titres of specific antibodies to Duffy Binding-Like (DBL)-5 during the third trimester of pregnancy and placental malaria. From this research, we found that this antibody type could therefore be used as biomarkers to predict the disease.
We have also approached (ii) the dynamics of naturally acquired antibodies to DBL5 and ID1-ID2a in primigravid women during.
We concluded that specific antibody levels to placental malaria decrease gradually in absence of placenta. Taking together, these results have motivated our desire to find an alternative diagnostic tool for detecting early in pregnancy, placental malaria before delivery, in order to provide better control the disease and ensure more successful pregnancy outcomes.
In parallel to my personal research activities, at IRSS-CRUN, I have been involved in several researches on malaria vaccines (RTS,S: a phase III clinical trial, and R21 phases II & III malaria vaccine trial).
My long-term career aspiration is to be established as an independent researcher and a leader in immunology.
Education – Nazi Boni University of Bobo-Dioulasso [2019] : PhD in Applied Biology (Immunology – Microbiology)
– Polytechnic University of Bobo-Dioulasso [2008] : Master of Science in Applied Biology and Biological Systems Modelling
– UFR/SVT, University of Ouagadougou [2005]: Master’s degree in Biochemistry/Food Technology and Human Nutrition
– UFR/SVT, University of Ouagadougou [2004]: Bachelor’s degree in Biochemistry/Food Technology and Human Nutrition
Experiences – January 2021- ongoing: Lab Manager in a phase III malaria vaccine trial (R21) Clinical Research Unit of Nanoro (CRUN), Burkina Faso
– January 2019- ongoing: Lab Manager in a phase Ib/IIb malaria vaccine trial (R21) Clinical Research Unit of Nanoro (CRUN), Burkina Faso
– Since October 2013- ongoing: Researcher Centre National de la Recherche Scientifique et Technologique (CNRST)
– Sept. 2011 – June 2018: Study Site Coordinator in a phase III malaria vaccine trial (RTS,S/AS01E) Clinical Research Unit of Nanoro (CRUN), Burkina Faso
– Since April 2011 – ongoing: Research assistant (for immunological studies) in the framework of GSK’s RTS,S/AS01E Clinical Research Unit of Nanoro (CRUN), Burkina Faso
– April 2009 – April 2011: Field supervisor in a phase III malaria vaccine trial (RTS,S/AS01E) Clinical Research Unit of Nanoro (CRUN), Burkina Faso
Awards / Honors Travel grants and scholarships:
– April 2018: Multilateral Initiative on Malaria (MIM) travel grant to attend to the 7th Multilateral Initiative on Malaria -Pan African Malaria Conference.
– October 2017: VLIR-UOS travel grant to attend to the International course in Epidemiology, Biostatistics & Qualitative research methods (EBQ), Antwerp, Belgium.
Research Grants 1. The National Fund for Research and Innovation for Development (FONRID Grants Programme 2021 funded. Estimation de l’efficacité vaccinale contre l’hépatite B : Prévalence de la séroprotection dans la région du Nord au Burkina Faso. Role: Co-Principal Investigator.
2. Royal Society of Tropical Medicine and Hygiene (RSTMH) Small Grants Programme 2021 funded (National Institute for Health Research (NIHR)). Tackling postpartum malaria: Effects of chemoprevention and treatment of pregnant women on parasites reservoir in the maternal and childhood environment. Role: Principal Investigator.
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