CRUN

Scientists

  • Innocent Valea - Medical Scientist / QA Manager

    Innocent Valea - Medical Scientist / QA Manager

    Research and professional experience :

    1. Personal Statement

    PharmD by background, he completed a MSc and a PhD in health biology and medical sciences, respectively. As a Medical Scientist, specialized in epidemiology and clinical research, he actively contributes to the design and implementation of research projects, including epidemiological studies and clinical trials on malaria and other infectious diseases. As ISO certified auditor for quality management systems, he has an oversight of the quality management system of the CRUN at the position of deputy head and QA manager. More than fifteen years’ experience in clinical research with a track record of more than 30 projects successfully implemented. Lecturer and consultant in monitoring/evaluation of health interventions and particularly malaria control programs. Actively involved in several health sciences research projects covering capacity building, community based interventions and product development. Specific interest on epidemiology, drugs and vaccines development for the control of infectious diseases and community based interventions to reduce child mortality. Strong expertise in implementing international research standards. Good skills and experience in networking and team building. Ten-year’s experience as deputy head of the Clinical Research Unit of Nanoro, Burkina Faso and two-year’s experience as Executive director of the National Centre for Research and Training on Malaria, Ministry of Health, Burkina Faso. Consultant for the World Health Organisation country office in Burkina Faso and associate lecturer of clinical research at University level.

    2. Positions and Employment :

    Since 2008 : Deputy Head/Quality assurance manager, Clinical Research Unit of Nanoro (IRSS/CRUN), Burkina Faso

    2016 - 2018. Executive Director, National Centre for Research and Training on Malaria (CNRFP), Ministry of Health, Burkina Faso,

    2008 - 2016 : Associate researcher, Department of Clinical Research, Centre Muraz, Bobo-Dioulasso-Burkina Faso,

    2005 - 2007 : Network Manager, West African Network 2 for monitoring antimalarial treatments (WANMAT2), Bobo-Dioulasso – Burkina Faso,

    2003 - 2005 : Pharmacist/Study monitor, Vaccinology and Epidemiology unit, Centre Muraz, Bobo-Dioulasso - Burkina Faso,

    Other Experience and Professional Memberships :

    Partnership for Increasing the Impact of Vector Control (PIIVeC)

    Société Burkinabé de Biologie Clinique

    African Society for Laboratory Medicine (ASLM)

    European Society for Medical Decision Making, (SMDM)

    American Society for Tropical Medicine and Hygiene (ASTMH)

    3. Selected Peer-reviewed Publication

    1: Skrip L, Derra K, Kaboré M, Noori N, Gansané A, Valéa I, Tinto H, Brice BW, Van Gordon M, Hagedorn B, Hien H, Althouse BM, Wenger EA, Ouédraogo AL. Clinical management and mortality among COVID-19 cases in sub-Saharan Africa: A retrospective study from Burkina Faso and simulated case analysis. Int J Infect Dis. 2020 Sep 25:S1201-9712(20)32148-2. doi: 10.1016/j.ijid.2020.09.1432. Epub ahead of print. PMID: 32987177; PMCID: PMC7518969.

    2: Bihoun B, Zango SH, Traoré-Coulibaly M, Valea I, Ravinetto R, Van Geertruyden JP, D'Alessandro U, Tinto H, Robert A. Fetal biometry assessment with Intergrowth 21st's and Salomon's equations in rural Burkina Faso. BMC Pregnancy Childbirth. 2020 Aug 26;20(1):492. doi: 10.1186/s12884-020-03183-5. PMID: 32847549; PMCID: PMC7449020.

    3: Sondo P, Derra K, Rouamba T, Nakanabo Diallo S, Taconet P, Kazienga A, Ilboudo H, Tahita MC, Valéa I, Sorgho H, Lefèvre T, Tinto H. Determinants of Plasmodium falciparum multiplicity of infection and genetic diversity in Burkina Faso. Parasit Vectors. 2020 Aug 20;13(1):427. doi: 10.1186/s13071-020-04302-z. PMID: 32819420; PMCID: PMC7441709.

    4: Rouamba T, Sondo P, Derra K, Nakanabo-Diallo S, Bihoun B, Rouamba E, Tarnagda Z, Kazienga A, Valea I, Sorgho H, Pagnoni F, Samadoulougou-Kirakoya F, Tinto H. Optimal Approach and Strategies to Strengthen Pharmacovigilance in Sub-Saharan Africa: A Cohort Study of Patients Treated with First-Line Artemisinin-Based Combination Therapies in the Nanoro Health and Demographic Surveillance System, Burkina Faso. Drug Des Devel Ther. 2020 Apr 16;14:1507-1521. doi: 10.2147/DDDT.S224857. PMID: 32368010; PMCID: PMC7174163.

    5: Birgersson S, Valea I, Tinto H, Traore-Coulibaly M, Toe LC, Hoglund RM, Van Geertruyden JP, Ward SA, D'Alessandro U, Abelö A, Tarning J. Population pharmacokinetics of artesunate and dihydroartemisinin in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Burkina Faso: an open label trial. Wellcome Open Res. 2019 Mar 7;4:45. doi: 10.12688/wellcomeopenres.14849.2. PMID: 32025570; PMCID: PMC6974929.

    6: Valéa I, Adjei S, Usuf E, Traore O, Ansong D, Tinto H, Owusu Boateng H, Some AM, Buabeng P, Vekemans J, Kotey A, Vandoolaeghe P, Cullinane M, Traskine M, Ouedraogo F, Sambian D, Lievens M, Tahita MC, Jongert E, Lompo P, Idriss A, Borys D, Ouedraogo S, Prempeh F, Schuerman L, Sorgho H, Agbenyega T. Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01 malaria vaccine in African children: a randomized trial. Hum Vaccin Immunother. 2020 Jun 2;16(6):1464-1470. doi: 10.1080/21645515.2019.1695457. Epub 2020 Jan 17. PMID: 31951771; PMCID:PMC7482624.

    7: Lingani M, Bonkian LN, Yerbanga I, Kazienga A, Valéa I, Sorgho H, Ouédraogo JB, Mens PF, Schallig HDFH, Ravinetto R, d'Alessandro U, Tinto H. In vivo/exvivo efficacy of artemether-lumefantrine and artesunate-amodiaquine as first-line treatment for uncomplicated falciparum malaria in children: an open label randomized controlled trial in Burkina Faso. Malar J. 2020 Jan 6;19(1):8. doi:10.1186/s12936-019-3089-z. PMID: 31906948; PMCID: PMC6945612.

    8: Tinto H, Otieno W, Gesase S, Sorgho H, Otieno L, Liheluka E, Valéa I, Sing'oei V, Malabeja A, Valia D, Wangwe A, Gvozdenovic E, Guerra Mendoza Y, Jongert E, Lievens M, Roman F, Schuerman L, Lusingu J. Long-term incidence of severe malaria following RTS,S/AS01 vaccination in children and infants in Africa: an open-label 3-year extension study of a phase 3 randomised controlled trial. Lancet Infect Dis. 2019 Aug;19(8):821-832. doi: 10.1016/S1473-3099(19)30300-7. Epub 2019 Jul 9. PMID: 31300331.

    9: Nambozi M, Tinto H, Mwapasa V, Tagbor H, Kabuya JB, Hachizovu S, Traoré M, Valea I, Tahita MC, Ampofo G, Buyze J, Ravinetto R, Arango D, Thriemer K, Mulenga M, van Geertruyden JP, D'Alessandro U. Artemisinin-based combination therapy during pregnancy: outcome of pregnancy and infant mortality: a cohort study. Malar J. 2019 Mar 28;18(1):105. doi: 10.1186/s12936-019-2737-7. PMID: 30922317; PMCID: PMC6437904.

    10: Unger H, Thriemer K, Ley B, Tinto H, Traoré M, Valea I, Tagbor H, Antwi G, Gbekor P, Nambozi M, Kabuya JB, Mulenga M, Mwapasa V, Chapotera G, Madanitsa M, Rulisa S, de Crop M, Claeys Y, Ravinetto R, D'Alessandro U. The assessment of gestational age: a comparison of different methods from a malaria pregnancy cohort in sub-Saharan Africa. BMC Pregnancy Childbirth. 2019 Jan 8;19(1):12. doi: 10.1186/s12884-018-2128-z. PMID: 30621604; PMCID: PMC6323786.

    11: Rouamba T, Valea I, Bognini JD, Kpoda H, Mens PF, Gomes MF, Tinto H, Kirakoya-Samadoulougou F. Safety Profile of Drug Use During Pregnancy at Peripheral Health Centres in Burkina Faso: A Prospective Observational Cohort Study. Drugs Real World Outcomes. 2018 Sep;5(3):193-206. doi: 10.1007/s40801-018-0141-1. PMID: 30155832; PMCID: PMC6119166.

    12: Bonkian LN, Yerbanga RS, Koama B, Soma A, Cisse M, Valea I, Tinto H, Ouedraogo JB, Guigemde TR, Traore/Coulibaly M. In Vivo Antiplasmodial Activity of Two Sahelian Plant Extracts on Plasmodium berghei ANKA Infected NMRI Mice. Evid Based Complement Alternat Med. 2018 May 24;2018:6859632. doi: 10.1155/2018/6859632. PMID: 29977316; PMCID: PMC5994278.

    13: Valéa I, Adjei S, Usuf E, Traore O, Ansong D, Tinto H, Owusu Boateng H, Leach A, Mwinessobaonfou Some A, Buabeng P, Vekemans J, Nana LA, Kotey A, Vandoolaeghe P, Ouedraogo F, Sambian D, Lievens M, Tahita MC, Rettig T, Jongert E, Lompo P, Idriss A, Borys D, Ouedraogo S, Prempeh F, Habib MA, Schuerman L, Sorgho H, Agbenyega T. Immune response to the hepatitis B antigen in the RTS,S/AS01 malaria vaccine, and co-administration with pneumococcal conjugate and rotavirus vaccines in African children: A randomized controlled trial. Hum Vaccin Immunother. 2018 Jun 3;14(6):1489-1500. doi:10.1080/21645515.2018.1442996. Epub 2018 Apr 13. PMID: 29630438; PMCID:PMC6037440.

    14: Cates JE, Unger HW, Briand V, Fievet N, Valea I, Tinto H, D'Alessandro U, Landis SH, Adu-Afarwuah S, Dewey KG, Ter Kuile FO, Desai M, Dellicour S, Ouma P, Gutman J, Oneko M, Slutsker L, Terlouw DJ, Kariuki S, Ayisi J, Madanitsa M, Mwapasa V, Ashorn P, Maleta K, Mueller I, Stanisic D, Schmiegelow C, Lusingu JPA, van Eijk AM, Bauserman M, Adair L, Cole SR, Westreich D, Meshnick S, Rogerson S. Malaria, malnutrition, and birthweight: A meta-analysis using individual participant data. PLoS Med. 2017 Aug 8;14(8):e1002373. doi: 10.1371/journal.pmed.1002373. PMID: 28792500; PMCID: PMC5549702.

    15: Unger HW, Cates JE, Gutman J, Briand V, Fievet N, Valea I, Tinto H, d'Alessandro U, Landis SH, Adu-Afarwuah S, Dewey KG, Ter Kuile F, Dellicour S, Ouma P, Slutsker L, Terlouw DJ, Kariuki S, Ayisi J, Nahlen B, Desai M, Madanitsa M, Kalilani-Phiri L, Ashorn P, Maleta K, Mueller I, Stanisic D, Schmiegelow C, Lusingu J, Westreich D, van Eijk AM, Meshnick S, Rogerson S. Maternal Malaria and Malnutrition (M3) initiative, a pooled birth cohort of 13 pregnancy studies in Africa and the Western Pacific. BMJ Open. 2016 Dec 21;6(12):e012697. doi:10.1136/bmjopen-2016-012697. PMID: 28003287; PMCID: PMC5223676.

    17: Tinto H, Valea I, Ouédraogo JB, Guiguemdé TR. Lessons learnt from 20 years surveillance of malaria drug resistance prior to the policy change in Burkina Faso. Ann Parasitol. 2016;62(1):17-24. doi: 10.17420/ap6201.27. PMID: 27262953.

    18: Baraka V, Tinto H, Valea I, Fitzhenry R, Delgado-Ratto C, Mbonye MK, Van Overmeir C, Rosanas-Urgell A, Van Geertruyden JP, D'Alessandro U, Erhart A. In vivo selection of Plasmodium falciparum Pfcrt and Pfmdr1 variants by artemether-lumefantrine and dihydroartemisinin-piperaquine in Burkina Faso. AntimicrobAgents Chemother. 2015 Jan;59(1):734-7. doi: 10.1128/AAC.03647-14. Epub 2014 Nov17. PMID: 25403659; PMCID: PMC4291431.

    19: Valea I, Tinto H, Traore-Coulibaly M, Toe LC, Lindegardh N, Tarning J, VanGeertruyden JP, D'Alessandro U, Davies GR, Ward SA. Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso. J Antimicrob Chemother. 2014 Sep;69(9):2499-507. doi: 10.1093/jac/dku154. Epub 2014 Jun 2. PMID: 24891429; PMCID: PMC4130382.

    20: Tinto H, Valea I, Sorgho H, Tahita MC, Traore M, Bihoun B, Guiraud I, Kpoda H, Rouamba J, Ouédraogo S, Lompo P, Yara S, Kabore W, Ouédraogo JB, Guiguemdé RT, Binka FN, Ogutu B. The impact of clinical research activities on communities in rural Africa: the development of the Clinical Research Unit of Nanoro (CRUN) in Burkina Faso. Malar J. 2014 Mar 22;13:113. doi: 10.1186/1475-2875-13-113. PMID: 24655351; PMCID: PMC3994337.

    4. Research Support

    ARES, Belgium: 2017 – 2021 : Amélioration de la santé maternelle et infantile par la prévention des co-infections paludisme et maladies sexuellement transmises chez les femmes enceintes au Burkina Faso (ARES), Principal Investigator

    Dalhousie University, Canada : 2016 – 2021 : A Phase 2 Randomized, Multi-Center Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Immunogenicity of 1 or 2 doses of the V920 (rVSVΔG-ZEBOV-GP) Ebola Virus Vaccine Candidate in HIV-Infected Adults and Adolescents (ACHIV-Ebola), Principal Investigator

    GSK Biologicals, Belgium : 2011 – 2017 : Malaria 63 Phase III randomized, open, controlled study to evaluate the immune response to the hepatitis B antigen of the RTS,S/AS01E candidate vaccine, when administered as primary vaccination with rotavirus vaccine and pneumococcal conjugate vaccine at 6, 10 and 14 weeks of age, to infants living in a malaria-endemic region in Africa, Principal investigator

  • Hermann Sorgho - Senior Research scientist

    Hermann Sorgho - Senior Research scientist

    Research and professional experience: 1. Positions and Employment

    Start date – End date:Postes

    2018 to present : Senior Research scientist, CRUN-IRSS, Institut de Recherche en Sciences de la Santé (IRSS), Burkina Faso

    2009 to present : Clinical trial coordinator (CRUN-IRSS Burkina Faso)

    2006 to present : Trainereffective project planning and evaluation in biomedical research” (WHO-TDR)

    2013 – 2014 : Temporary advisor “mapping of neglected tropical diseases” (WHO-Afro)

    2006 – 2008 : Research fellow(IRSS-Bobo-Dioulasso)

    2000 – 2006 : PhD candidate (University of Ouagadougou, Burkina Faso)    

    2. Personal Statemen

    (provide a short description of your research interest and/or motivation/ fournir une brève description de vos centres d’intérêt et/ou motivation)

    My main area of interest in research covers human immune response to parasitic infection and parasitic diseases and control through vaccination. I worked on several research projects on the control of malaria and schistosomiasis.

    Recently I invested some effort in public health approaches to improve health during the early infancy and also in understanding the interactions between genomic and environmental factors that influence health in early infancy and late adulthood.

    Other Experience and Professional Memberships

    Start date – End date    

    3. Selected Peer-reviewed Publications

    Watson D, Kehoe SH, Erzse A, Compaoré A, Debpuur C, Nonterah EA, Sorgho H, Norris SA, Hofman KJ, Lawrence W, Newell ML, Godfrey KM, Ward KA, Barker M; INPreP group. (2020). Community perspectives on maternal and child health during nutrition and economic transition in sub-Saharan Africa. Public Health Nutrition 2020 Sep 15:1-9.   doi: 10.1017/S1368980020003018

    Boua PR, Brandenburg JT, Choudhury A, Hazelhurst S, Sengupta D, Agongo G, Nonterah EA, Oduro AR, Tinto H, Mathew CG, Sorgho H, Ramsay M. (2020). Novel and known gene-smoking interactions with cIMT identified as potential drivers for atherosclerosis risk in West-African populations of the AWI-Gen study. Frontiers in Genetics. 2020 Feb 7;10:1354.   doi: 10.3389/fgene.2019.01354

    George JA, Brandenburg JT, Fabian J, Crowther NJ, Agongo G, Alberts M, Ali S, Asiki G, Boua PR, Gómez-Olivé FX, Mashinya F, Micklesfield L, Mohamed SF, Mukomana F, Norris SA, Oduro AR, Soo C, Sorgho H, Wade A, Naicker S, Ramsay M; AWI-Gen and the H3Africa Consortium. (2019). Kidney damage and associated risk factors in rural and urban sub-Saharan Africa (AWI-Gen): a cross-sectional population study. Lancet Global Health. 2019 Dec;7(12):e1632-e1643. doi: 10.1016/S2214-109X(19)30443-7

    Ali SA, Soo C, Agongo G, Alberts M, Amenga-Etego L, Boua RP, Choudhury A, Crowther NJ, Depuur C, Gómez-Olivé FX, Guiraud I, Haregu TN, Hazelhurst S, Kahn K, Khayeka-Wandabwa C, Kyobutungi C, Lombard Z, Mashinya F, Micklesfield L, Mohamed SF, Mukomana F, Nakanabo-Diallo S, Natama HM, Ngomi N, Nonterah EA, Norris SA, Oduro AR, Somé AM, Sorgho H, Tindana P, Tinto H, Tollman S, Twine R, Wade A, Sankoh O, Ramsay M. (2018). Genomic and environmental risk factors for cardiometabolic diseases in Africa: methods used for Phase 1 of the AWI-Gen population cross-sectional study. Global Health Action. 2018;11(sup2):1507133. doi: 10.1080/16549716.2018.1507133.

    Boua RP, Sorgho H, Rouamba T, Nakanabo Diallo S, Bognini JD, Konkobo SZ, Valia D, Lingani M, Ouoba S, Tougma AS, Bihoun B, Crowther NJ, Norris SA, Ramsay M, Tinto H; as members of AWI-Gen and the H3Africa Consortium. (2018). Gender differences in sociodemographic and behavioural factors associated with BMI in an adult population in rural Burkina Faso - an AWI-Gen sub-study. Global Health Action. 2018;11(sup2):1527557. doi: 10.1080/16549716.2018.1527557.

    Ramsay M, Crowther NJ, Agongo G, Ali SA, Asiki G, Boua RP, Gómez-Olivé FX, Kahn K, Khayeka-Wandabwa C, Mashinya F, Micklesfield L, Mukomana F, Nonterah EA, Soo C, Sorgho H, Wade AN, Wagner RG, Alberts M, Hazelhurst S, Kyobutungi C, Norris SA, Oduro AR, Sankoh O, Tinto H, Tollman S & as members of AWI-Gen and the H3Africa Consortium (2018). Regional and sex-specific variation in BMI distribution in four sub-Saharan African countries: The H3Africa AWI-Gen study. Global Health Action. 2018;11(sup2):1556561. doi: 10.1080/16549716.2018.1556561

    Gómez-Olivé FX, Ali SA, Made F, Kyobutungi C, Nonterah E, Micklesfield L, Alberts M, Boua R, Hazelhurst S, Debpuur C, Mashinya F, Dikotope S, Sorgho H, Cook I, Muthuri S, Soo C, Mukomana F, Agongo G, Wandabwa C, Afolabi S, Oduro A, Tinto H, Wagner RG, Haregu T, Wade A, Kahn K, Norris SA, Crowther NJ, Tollman S, Sankoh O, Ramsay M; as members of AWI-Gen and the H3Africa Consortium. (2017). Regional and sex differences in the prevalence and awareness of hypertension: An H3Africa AWI-Gen study across 6 sites in Sub-Saharan Africa. Global Heart. 2017 Jun;12(2):81-90. doi: 10.1016/j.gheart.2017.01.007

    H3Africa Consortium (2014). Research capacity. Enabling the genomic revolution in Africa. Science. 2014 Jun 20;344(6190):1346-8. doi: 10.1126/science.1251546

    Valéa I, Adjei S, Usuf E, Traore O, Ansong D, Tinto H, Owusu Boateng H, Some AM, Buabeng P, Vekemans J, Kotey A, Vandoolaeghe P, Cullinane M, Traskine M, Ouedraogo F, Sambian D, Lievens M, Tahita MC, Jongert E, Lompo P, Idriss A, Borys D, Ouedraogo S, Prempeh F, Schuerman L, Sorgho H, Agbenyega T. (2020).Long-term immunogenicity and immune memory response to the hepatitis B antigen in the RTS,S/AS01E malaria vaccine in African children: a randomized trial. Human Vaccines and Immunotherapeutics. 2020 Jun 2;16(6):1464-1470.   doi: 10.1080/21645515.2019.1695457

    Sondo P, Derra K, Rouamba T, Nakanabo Diallo S, Taconet P, Kazienga A, Ilboudo H, Tahita MC, Valéa I, Sorgho H, Lefèvre T, Tinto H. (2020). Determinants of Plasmodium falciparum multiplicity of infection and genetic diversity in Burkina Faso. Parasites and Vectors. 2020 Aug 20;13(1):427.   doi: 10.1186/s13071-020-04302-z

    Sondo P, Derra K, Lefevre T, Diallo-Nakanabo S, Tarnagda Z, Zampa O, Kazienga A, Valea I, Sorgho H, Ouedraogo JB, Guiguemde TR, Tinto H. (2019). Genetically diverse Plasmodium falciparum infections, within-host competition and symptomatic malaria in humans. Scientific Reports. 2019 Jan 15;9(1):127.   doi: 10.1038/s41598-018-36493-y.

    Dobaño C, Sanz H, Sorgho H, Dosoo D, Mpina M, Ubillos I, Aguilar R, Ford T, Díez-Padrisa N, Williams NA, Ayestaran A, Traore O, Nhabomba AJ, Jairoce C, Waitumbi J, Agnandji ST, Kariuki S, Abdulla S, Aponte JJ, Mordmüller B, Asante KP, Owusu-Agyei S, Tinto H, Campo JJ, Moncunill G, Gyan B, Valim C, Daubenberger C. (2019). Concentration and avidity of antibodies to different circumsporozoite epitopes correlate with RTS,S/AS01E malaria vaccine efficacy. Nature Communications. 2019 May 15;10(1):2174.   doi: 10.1038/s41467-019-10195-z.

    Tinto H, Otieno W, Gesase S, Sorgho H, Otieno L, Liheluka E, Valéa I, Sing'oei V, Malabeja A, Valia D, Wangwe A, Gvozdenovic E, Guerra Mendoza Y, Jongert E, Lievens M, Roman F, Schuerman L, Lusingu J. (2019). Long-term incidence of severe malaria following RTS,S/AS01 vaccination in children and infants in Africa: an open-label 3-year extension study of a phase 3 randomised controlled trial. Lancet Infectious Diseases. 2019 Aug;19(8):821-832.   doi: 10.1016/S1473-3099(19)30300-7

    Early AM, Lievens M, MacInnis BL, Ockenhouse CF, Volkman SK, Adjei S, Agbenyega T, Ansong D, Gondi S, Greenwood B, Hamel M, Odero C, Otieno K, Otieno W, Owusu-Agyei S, Asante KP, Sorgho H, Tina L, Tinto H, Valea I, Wirth DF, Neafsey DE. (2018). Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections. Nature Communications. 2018 Apr 11;9(1):1381. doi: 10.1038/s41467-018-03807-7.

    Natama HM, Rovira-Vallbona E, Somé MA, Zango SH, Sorgho H, Guetens P, Coulibaly-Traoré M, Valea I, Mens PF, Schallig HDFH, Kestens L, Tinto H, Rosanas-Urgell A. (2018). Malaria incidence and prevalence during the first year of life in Nanoro, Burkina Faso: a birth-cohort study. Malaria Journal. 2018 Apr 12;17(1):163. doi: 10.1186/s12936-018-2315-4.

    Natama HM, Rovira-Vallbona E, Sorgho H, Somé MA, Traoré-Coulibaly M, Scott S, Zango SH, Sawadogo O, Zongo SC, Valéa I, Mens PF, Schallig HDFH, Kestens L, Tinto H, Rosanas-Urgell A. (2018). Additional screening and treatment of malaria during pregnancy provides further protection against malaria and nonmalarial fevers during the first year of life. Journal of Infectious Diseases. 2018 May 25;217(12):1967-1976. doi: 10.1093/infdis/jiy140.

    Valéa I, Adjei S, Usuf E, Traore O, Ansong D, Tinto H, Owusu Boateng H, Leach A, Mwinessobaonfou Some A, Buabeng P, Vekemans J, Nana LA, Kotey A, Vandoolaeghe P, Ouedraogo F, Sambian D, Lievens M, Tahita MC, Rettig T, Jongert E, Lompo P, Idriss A, Borys D, Ouedraogo S, Prempeh F, Habib MA, Schuerman L, Sorgho H, Agbenyega T. (2018). Immune response to the hepatitis B antigen in the RTS,S/AS01 malaria vaccine, and co-administration with pneumococcal conjugate and rotavirus vaccines in African children: A randomized controlled trial. Human Vaccines and Immunotherapeutics. 2018 Jun 3;14(6):1489-1500.   doi: 10.1080/21645515.2018.1442996

    Ubillos I, Ayestaran A, Nhabomba AJ, Dosoo D, Vidal M, Jiménez A, Jairoce C, Sanz H, Aguilar R, Williams NA, Díez-Padrisa N, Mpina M, Sorgho H, Agnandji ST, Kariuki S, Mordmüller B, Daubenberger C, Asante KP, Owusu-Agyei S, Sacarlal J, Aide P, Aponte JJ, Dutta S, Gyan B, Campo JJ, Valim C, Moncunill G, Dobaño C. (2018). Baseline exposure, antibody subclass, and hepatitis B response differentially affect malaria protective immunity following RTS,S/AS01E vaccination in African children. BMC Medicine. 2018 Oct 31;16(1):197. doi: 10.1186/s12916-018-1186-4

    Natama HM, Moncunill G, Rovira-Vallbona E, Sanz H, Sorgho H, Aguilar R, Coulibaly-Traoré M, Somé MA, Scott S, Valéa I, Mens PF, Schallig HDFH, Kestens L, Tinto H, Dobaño C, Rosanas-Urgell A. (2018). Modulation of innate immune responses at birth by prenatal malaria exposure and association with malaria risk during the first year of life. BMC Medicine. 2018 Nov 2;16(1):198. doi: 10.1186/s12916-018-1187-3

    Sorgho H, Douamba KRD, Valea I, Tinto H. (2017). Performance diagnostique de SD Bioline malaria antigen P.f® pour la détection des infections palustres chez la femme enceinte au troisième trimestre de grossesse au Burkina Faso. Science et Technique, Sciences de la santéVol. 40, n°2, 81-87.

    Natama HM, Ouedraogo DF, Sorgho H, Rovira-Vallbona E, Serra-Casas E, Somé MA, Coulibaly-Traoré M, Mens PF, Kestens L, Tinto H, Rosanas-Urgell A. (2017). Diagnosing congenital malaria in a high-transmission setting: clinical relevance and usefulness of P. falciparum HRP2-based testing. Scientific Reports, 2017 May 18;7(1):2080. doi: 10.1038/s41598-017-02173-6.

    Somé AF, Sorgho H, Zongo I, Bazié T, Nikiéma F, Sawadogo A, Zongo M, Compaoré YD, Ouédraogo JB. (2016). Polymorphisms in K13, pfcrt, pfmdr1, pfdhfr, and pfdhps in parasites isolated from symptomatic malaria patients in Burkina Faso. Parasite. 2016; 23:60. doi: 10.1051/parasite/2016069.

    Tinto H, Sombié O, Valea I, Lankoandé F, Yara S, Lompo P, Tahita MC, Kazienga A, Ouédraogo S, Sorgho H, De Crop M, Ravinetto R. (2015). Field evaluation of SD-Bioline malaria antigen P.f® for Plasmodium falciparum malaria diagnosis in Nanoro, Burkina Faso. African Journal of Parasitology Research, 4 (11), 161-165.

    Sondo P, Valea I, Biebo B, Sorgho H, Kazienga A, Ouedraogo J-B, Guiguemdé TR, Tinto H. (2015). La part du paludisme dans les maladies fébriles en saison sèche dans la région de Nanoro, Burkina Faso. West African Medical Journal, Jun 9;21:101. doi: 10.11604/pamj.2015.21.101.6437. eCollection 2015.

    Neafsey DE, Juraska M, Bedford T, Benkeser D, Valim C, Griggs A, Lievens M, Abdulla S, Adjei S, Agbenyega T, Agnandji ST, Aide P, Anderson S, Ansong D, Aponte JJ, Asante KP, Bejon P, Birkett AJ, Bruls M, Connolly KM, D'Alessandro U, Dobaño C, Gesase S, Greenwood B, Grimsby J, Tinto H, Hamel MJ, Hoffman I, Kamthunzi P, Kariuki S, Kremsner PG, Leach A, Lell B, Lennon NJ, Lusingu J, Marsh K, Martinson F, Molel JT, Moss EL, Njuguna P, Ockenhouse CF, Ogutu BR, Otieno W, Otieno L, Otieno K, Owusu-Agyei S, Park DJ, Pellé K, Robbins D, Russ C, Ryan EM, Sacarlal J, Sogoloff B, Sorgho H, Tanner M, Theander T, Valea I, Volkman SK, Yu Q, Lapierre D, Birren BW, Gilbert PB, Wirth DF. (2015). Genetic diversity and protective efficacy of the RTS,S/AS01 malaria vaccine. New England Journal of Medicine, 2015 (373) 21: 2025-2037. doi: 10.1056/NEJMoa1505819.

    White MT, Verity R, Griffin JT, Asante KP, Owusu-Agyei S, Greenwood B, Drakeley C, Gesase S, Lusingu J, Ansong D, Adjei S, Agbenyega T, Ogutu B, Otieno L, Otieno W, Agnandji ST, Lell B, Kremsner P, Hoffman I, Martinson F, Kamthunzu P, Tinto H, Valea I, Sorgho H, Oneko M, Otieno K, Hamel MJ, Salim N, Mtoro A, Abdulla S, Aide P, Sacarlal J, Aponte JJ, Njuguna P, Marsh K, Bejon P, Riley EM, Ghani AC. (2015). Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: secondary analysis of data from a phase 3 randomised controlled trial. Lancet Infectious Diseases, 15: 1450–1458. doi: 10.1016/S1473-3099(15)00239-X

    RTS,S Clinical Trials Partnership (2015). Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. Lancet, 2015 Jul 4;386(9988):31-45. doi: 10.1016/S0140-6736(15)60721-8.

    Tinto H, Valea I, Sorgho H, Tahita MC, Traore M, Bihoun B, Guiraud I, Kpoda H, Rouamba J, Ouédraogo S, Lompo P, Yara S, Kabore W, Ouédraogo JB, Guiguemdé RT, Binka FN, Ogutu B. (2014) The impact of clinical research activities on communities in rural Africa: the development of the clinical research unit of Nanoro (CRUN) in Burkina Faso. Malaria Journal. 2014 Mar 22;13:113. doi: 10.1186/1475-2875-13-113

    RTS,S Clinical Trials Partnership (2012). A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants. New England Journal of Medicine, 2012 Dec 13;367(24):2284-95.   doi: 10.1056/NEJMoa1208394.

    RTS, S Clinical Trials Partnership (2011). First results of phase 3 Trial of RTS,S/AS01 malaria vaccine in African children.New England Journal of Medicine 17;365(20):1863-75. doi: 10.1056/NEJMoa1102287

    Valea I, Tinto H, Drabo MK, Huybregts L, Sorgho H, Ouedraogo JB, Guiguemde RT, van Geertruyden JP, Kolsteren P, D'Alessandro U; FSP/Misame Study Group (2012). An analysis of timing and frequency of malaria infection during pregnancy in relation to the risk of low birth weight, anaemia and perinatal mortality in Burkina Faso. Malaria Journal2012 Mar 16;11:71. doi: 10.1186/1475-2875-11-71.

    Zeba AN, Sorgho H, Rouamba N, Zongo I, Rouamba J, Guiguemdé RT, Hamer DH, Mokhtar N, Ouedraogo JB. (2008). Major reduction of malaria morbidity with combined vitamin A and zinc supplementation in young children in Burkina Faso: a randomized double-blind trial. Nutrition Journal, 31, 7:7.   doi: 10.1186/1475-2891-7-7

    Sorgho H, Da O, Rouamba T, Savadogo B, Tinto H, Ouedraogo J-B. (2017). Schistosoma mansoni infection and hematological profile in an endemic foci in Western Burkina Faso. African Journal of Parasitology Research, 4 (10), 264-270.

    Bagayan M, Zongo D, Oueda A, Sorgho H, Savadogo B, Drabo F, Ouedraogo A, Poda JN, Kabre BG, Zhang Y. (2016). Prevalence of schistosomiasis and soil-transmitted helminth infections among schoolchildren in Burkina Faso. Médecine et Santé Tropicale. 2016 Aug 1;26(3):267-272.   doi: 10.1684/mst.2016.0570

    Bagayan M, Zongo D, Ouéda A, Savadogo B, Sorgho H, Drabo F, Ouédraogo A, Bamba I, Zhang Y, Kabré GB, Poda JN. (2015). Prevalence of Hymenolepis nana among primary school children in Burkina Faso. International Journal of Medicine and Medical Sciences. 7(10): 148-153, December 2015.  doi: 10.5897/IJMMS2015.1179

    Kpoda NW, Sorgho H, Poda JN, Ouédraogo JB, Kabré GB. (2013). Schistosomiasis caused by Schistosoma mansoni in the Kou valley: Characterization of the transmission system and socioeconomic impact. Comptes Rendus Biologies 2013 May-Jun;336(5-6):284-8. doi: 10.1016/j.crvi.2013.04.008.

    Bahgat M, Sorgho H, Ouédraogo JB, Poda JN, Sawadogo L, Ruppel A. (2006).Enzyme-linked immunosorbent assay with worm vomit and cercarial secretions of Schistosoma mansoni to detect infections in an endemic focus of Burkina Faso.Journal of Helminthology, 80, 19-23.   doi: 10.1079/joh2005312

    Sorgho H., Bahgat M., Poda J-N, Song W, Kirsten C, Doenhoff MJ., Zongo I, Ouédraogo J-B, Ruppel A. (2005). Serodiagnosis of Schistosoma mansoni infections in an endemic area of Burkina Faso : performance of several immunological tests with different parasite antigens. Acta Tropica, 93, 169-180.   doi: 10.1016/j.actatropica.2004.10.006

    Poda JN, Wango SP, Sorgho H, Dianou D. (2004). Evolution récente des schistosomoses dans le complexe hydroagricole du Sourou au Burkina Faso. Bulletin de la Société de Pathologie Exotique, 97, 1, 15-18.

    Dianou D, odaJN P, Sorgho H, Wango SP, Sondo KB. (2003). Hydraulic plannings and Schistosomiasis: Case of Sourou in Burkina Faso. Journal of Applied Research in Veterinary Medicine, 1, 2, 105-111.  

    4. Research Support

    (Sponsor-Start date – End date: Position) /(Structure de financement-Début-Fin): Postes

    Study of immune correlates of protection against malaria after vaccination with RTS, S/AS01E. MVI funded. 2010 – 2013. Principal Investigator

    Understanding RTS,S malaria vaccine-induced protection through integrated analysis. NIH funded. 2013 – 2018. Principal Investigator

    Genomic and environmental risk factors for cardiometabolic diseases in Africans. NIH funded. 2014 – 2021. Co-Principal Investigator

    Leveraging improved nutrition preconception, during pregnancy and postpartum in Sub-Saharan Africa through novel intervention models. NIHR funded. 2018 – 2022. Principal Investigator
  • Hamtandi M. Natama - Associate Researcher

    Hamtandi M. Natama - Associate Researcher

    strong>Research and professional experience:

     

    1. Personal Statement

    I am a biomedical scientist holding a PhD awarded by the University of Antwerp (Belgium) in 2018. I have 14 years experience in malaria research, which started in 2006 when I was preparing my Master thesis in Applied Biological Sciences at University of Ouagadougou (Burkina Faso). Before starting my PhD training, I participated in several malaria research projects in Burkina Faso and in Japan. Between 2014-2018, I carried out my PhD project entitled “Genetic and immunological factors contributing to inter-individual variation in susceptibility to malaria in early infancy” under the supervision of Prof. Halidou Tinto (CRUN, Burkina Faso), Prof. Anna Rosanas-Urgell (ITM, Belgium) and Prof. Luc Kestens (University of Antwerp, Belgium). My current research interest is to understand how placental malaria drives heterogeneity in immune responses to pathogens molecules/malaria antigens and, influences the build up of naturally acquired immunity during the first year of life. I am also involved in a clinical trial assessing a candidate malaria vaccine known as R21. My field of expertise includes malaria epidemiology, immune responses to malaria, Human genetics and malaria susceptibility.

     

    2. Positions and Employment

    Since 17/07/2019 : Associate researcher

    27/02/2019- 16/07/2019 : Research assistant

    01/10/2013- 26/02/2019 : Research engineer

    Other Experience and Professional Memberships

    01/01/2014- 13/12/2018 : PhD fellow  at the Institute of Tropical Medicine, Antwerp (Belgium)

     

    3. Selected Peer-reviewed Publications

    Natama HM, Moncunill G, Rovira-Vallbona E, Sanz H, Sorgho H, Aguilar R, Coulibaly-Traoré M, Somé MA; Susana Scott,Innocent Valéa, Petra F. Mens,Henk D.F.H Schallig, Luc Kestens, Halidou Tinto, Carlota Dobaño, Anna Rosanas-Urgell. Modulation of innate immune responses at birth by prenatal malaria exposure and association with malaria risk during the first year of life. BMC Medicine (2018), 16 :198. DOI: 10.1186/s12916-018-1187-3.

    Natama HM, Rovira-Vallbona E, Somé MA, Zango SH, Sorgho H, Guetens P, Coulibaly-Traoré M, Valéa I, Mens PF, Schallig HDFH, Kestens L, Tinto H, Rosanas-Urgell A. Malaria incidence and prevalence during the first 12 months of life in Burkina Faso: a birth-cohort study. Malaria Journal (2018); 17:163

    Natama HM, Rovira-Vallbona E, Sorgho H, Somé MA, Coulibaly-Traoré M, Scott S, Zango SH, Sawadogo O, Zongo SC, Valéa I, Mens PF, Schallig HDFH, Kestens L, Tinto H, Rosanas-Urgell A. Additional screening and treatment of malaria during pregnancy provides further protection against malaria and non-malaria fevers during the first year of life. Journal of Infectious Diseases (2018), jiy140, https://doi.org/10.1093/infdis/jiy140.

    Natama HM, Ouedraogo DF, Sorgho H, Rovira-Vallbona E, Sera-Casas E, Somé MA, Coulibaly-Traoré M, Mens PF, Kestens L, Tinto H, Rosanas-Urgell A: Diagnosing congenital malaria in a high-transmission setting: clinical relevance and usefulness of P. falciparum HRP2-based testing. Scientific Reports (2017), 7(1): 2080. DOI: 10.1038/s41598-017-02173-6.

    Herbas MS, Natama HM and Suzuki H. Alpha tocopherol transfer protein gene inhibition enhances the acquired immune response during malaria infection in mice. Parasitology Research (2014) 113(3): 1019. DOI 10.1007/s00436-013-3736-1.

     

    4. Research Support

    (Sponsor-Start date – End date: Position) /(Structure de financement-Début-Fin): Postes

    PhD fellowship (01/01/2014-13/12/2018) /Belgian Development Cooperation-DGD (collaboration CRUN-ITM, Framework agreement 3 & 4): PhD fellow

    AREF-EDCTP preparatory fellowship (01/05/2021-31/10/2021)/ European and Developing Countries Clinical Trials Partnership: Postdoc fellow

  • Hamidou Ilboudo - Associate Researcher

    Hamidou Ilboudo - Associate Researcher

    Research and professional experience:

    1. Personal Statement

    My research career started in 2006 when I joined the “Institut de Recherche en Sciences de la Sante (IRSS)" in Bobo Dioulasso (Burkina Faso) working on the impact of the polymorphism of the kdr gene on the biting behaviour of the molecular form M of Anopheles gambiae in response to repellents which was a hugely enjoyable and rewarding time and fired my enthusiasm for research. After completing my MSc in 2007, I decided to apply the skills and techniques I had developed to the study of human African trypanosomiasis (HAT) for my PhD so I moved to “Centre International de Recherche-Développement sur l’Elevage en Zone Subhumide" ((CIRDES), Burkina-Faso and obtained my PhD in 2012 awarded by the Polytechnic University of Bobo-Dioulasso (Burkina-Faso). For my thesis, I performed a better phenotypic characterization of the clinical diversity observed in HAT, in particular the existence of trypanotolerant individuals able to control infection. I also showed for the first time, through immunological studies that the nature of the immune response is very different between the susceptible individuals (HAT patients) and individuals who resist naturally to infection. After my PhD, I undertook post-doctoral studies in CIRDES (May 2012-June 2017) on the host genetic susceptibility in HAT within the TrypanoGEN project funded by the Wellcome Trust. For my post-doctoral, I showed that APOL1 polymorphisms (G1, G2) are associated with HAT. In July 2017, I joined the Institut de Recherche pour le Développement” (IRD) as post-doctoral researcher and based in Guinea National control program against HAT where I has been working on elimination of HAT in Guinea HAT foci. These successes favoured my recruitment at the IRSS/ “Unité de Recherche Clinique de Nanoro (URCN) as permanent researcher in November 2017.

     

    2. Positions and Employment

    -Since November 2017 : permanent position at the Institut de Recherche en Science de la Santé (IRSS) / Unité de Recherche Clinique de Nanoro (URCN)

    -From July 2017 to October 2017: post-doctoral researcher at the “Institut de Recherche pour le Développement” (IRD) based to the Guinea National control program against HAT(Conakry).

    -From May 2012 to June 2017: Researcher at the CIRDES

    Other Experience and Professional Memberships

    Member of WHO Collaborating Center for research on host/vector/parasite interactions for surveillance and control of Human African Trypanosomiasis

    3. Selected Peer-reviewed Publications 

    Mulindwa J, Noyes H, Ilboudo H, Pagani L, Nyangiri O, Kimuda MP, Ahouty B, Asina OF, Ofon E, Kamoto K, Kabore JW, Koffi M, Ngoyi DM, Simo G, Chisi J, Sidibe I, Enyaru J, Simuunza M, Alibu P, Jamonneau V, Camara M, Tait A, Hall N, Bucheton B, MacLeod A, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group of the H3Africa Consortium. High Levels of Genetic Diversity within Nilo-Saharan Populations: Implications for Human Adaptation. Am J Hum Genet. 2020 Sep 3;107(3):473-486. doi: 10.1016/j.ajhg.2020.07.007. Epub 2020 Aug 10.

    Nyangiri OA, Noyes H, Mulindwa J, Ilboudo H, Kabore JW, Ahouty B, Koffi M, Asina OF, Mumba D, Ofon E, Simo G, Kimuda MP, Enyaru J, Alibu VP, Kamoto K, Chisi J, Simuunza M, Camara M, Sidibe I, MacLeod A, Bucheton B, Hall N, Hertz-Fowler C, Matovu E; TrypanoGEN Research Group, as members of The H3Africa Consortium. Copy number variation in human genomes from three major ethno-linguistic groups in Africa. BMC Genomics. 2020 Apr 10;21(1):289. doi: 10.1186/s12864-020-6669-y.

     

    2019

    Dama E, Camara O, Kaba D, Koffi M, Camara M, Compaoré C, Ilboudo H, Courtin F, Kaboré J, N'Gouan EK, Büscher P, Lejon V, Bucheton B, Jamonneau V. Immune trypanolysis test as a promising bioassay to monitor the elimination of gambiense human African trypanosomiasis. Parasite. 2019;26:68. doi: 10.1051/parasite/2019066. Epub 2019 Nov 22

    Kaboré JW, Camara O, Ilboudo H, Capewell P, Clucas C, Cooper A, Kaboré J, Camara M, Jamonneau V, Hertz-Fowler C, Bélem AMG, Matovu E, Macleod A, Sidibé I, Noyes H, Bucheton B ; TrypanoGEN Research Group, as member of the H3Africa Consortium. Macrophage migrating inhibitory factor expression is associated with Trypanosoma brucei gambiense infection and is controlled by trans-acting expression quantitative trait loci in the Guinean population. Infect Genet Evol. 2019 Mar 23;71:108-115. doi: 10.1016/j.meegid.2019.03.021.

    2018

    informal Expert Group on Gambiense HAT Reservoirs, Büscher P, Bart J-M, Boelaert M, Bucheton B, Chitnis N, Courtin D, Figueiredo LM, Franco J-R, Grébaut P, Hasker E, Ilboudo H, Jamonneau V, Koffi M, Lejon V, MacLeod A, Masumu J, Matovu E, Mattioli R, Noyes H, Picado A, Rock KS, Rotureau B, Simo G, Thévenon S, Trindade S, Truc P, Reet VN (informal expert group gambiense reservoirs). Do cryptic reservoir threaten gambiense-sleeping sickness elimination? Trends in parasitology. ttp://dx.doi.org/10.1016/j.pt.2017.11.008

    2017

    N’Djetch MK, Ilboudo H, Koff M, Kaboré J, Kaboré J, Kaba D, Courtin F, Bamoro C, Fauret P, Kouakou L, Ravel S, Deborggraeve S, Solano P, De Meeûs T, Bucheton B, Jamonneau V. The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Côte d'Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense. LoS Negl Trop Dis 11(10): e0005993. https://doi.org/10.1371/journal.pntd.0005993

    Bernadin A, Koffi M, Ilboudo H, Simo G, Matovu E, Mulindwa J, Hertz-Fowler C, Bucheton B, Sidibé I, Jamonneau V, MacLeod A, Noyes H, N’Guetta1 SP, for the TrypanoGEN Research Group as members of The H3Africa Consortium. Candidate genes-based investigation of susceptibility to Human African. PLoS Negl Trop Dis. 2017 Oct 23;11(10):e0005992. doi: 10.1371/journal.pntd.0005992

    Kaboré JW, Ilboudo H, Noyes H, Camara O, Kaboré J, Camara M, Koffi M, Lejon V, Jamonneau V, MacLeod A, Hertz-Fowler C, Belem AMG, Matovu E, Bucheton B, Sidibé I, TrypanoGEN Research Group as members of the H3Africa Consortium. Candidate gene polymorphisms study between human African trypanosomiasis clinical phenotypes in Guinea. PLoS Negl Trop Dis 11(8): e0005833. https://doi.org/10.1371/journal.pntd.0005833.

    Ilboudo H, Noyes H, Mulindwa J, Kimuda MP, Koffi M, Kaboré JW, Ahouty B, Ngoyi DM, Fataki O, Simo G, Ofon E, Enyaru J, Chisi J, Kamoto K, Simuunza M, Alibu VP, Lejon V, Jamonneau V, Macleod A, Camara M, Bucheton B, Hertz-Fowler C, Sidibe I, Matovu E; TrypanoGEN Research Group as members of The H3Africa Consortium. Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis. PLoS Negl Trop Dis. 2017 Jun 1;11(6):e0005438. doi: 10.1371/journal.pntd.0005438. eCollection 2017 Jun.

    Cooper A, Ilboudo H, Alibu VP, Ravel S, Enyaru J, Weir W, Noyes H, Capewell P, Camara M, Milet J, Jamonneau V, Camara O, Matovu E, Bucheton B, MacLeod. APOL1 renal risk variants have contrasting resistance and susceptibility associations with African trypanosomiasis. Elife. 2017 May 24;6. pii: e25461. doi: 10.7554/eLife.25461.

    2016

    Ilboudo H, Jamonneau V, Koffi M, Kaboré J, Amoussa R, Holzmuller P, Garcia A, Bucheton B, Courtin D. Trypanosome-induced Interferon-γ production in whole blood stimulation assays is associated with latent Trypanosoma brucei gambiense infections. Microbes Infect. 2016 Jun;18(6):436-40. doi: 10.1016/j.micinf.2016.03.002. Epub 2016 Mar 16.

    2015

    Ilboudo H, Camara O, Ravel S, Bucheton B, Lejon V, Camara M, Kaboré J, Jamonneau V, Deborggraeve S (2015). The trypanosome’s spliced leader RNA is a more specific marker for cure of human African trypanosomiasis than DNA. (DOI: 10.1093/infdis/jiv337).

     

    4. Research Support

    Wellcome Trust. 2018-2021. TrypanoGEN +. The genetic determinant of two neglected tropical diseases (human African trypanosomiasis and schistosomiasis). Collaborator.

    European and Developing Countries Clinical Trials Partnership (EDCTP). 2016-2019. Diagnostic tools for human African trypanosomiasis elimination and clinical trials (DiTECT)-HAT. Co-Pi

    Wellcome Trust, H3Africa. 2012-2018. TrypanoGEN: an integrated approach to identification of genetic determinants of susceptibility to trypanosomiasis. Participant.

    “Institut de Recherche pour le Développement (IRD) /Jeune Equipe Associée de I’IRD (JEAI)”. 2014-2017. Epidemiological study of the role of trypanotolerant individual and domestic animals in maintaining the transmission of T. b. gambiense in West and Central Ivory Coast foci. Co-pi.

    “Union Economique et Monétaire Ouest Africaine (UEMOA) /Programme d’Appui à l’Enseignement Supérieur (PAES). 2013-2014. The role of domestic animals in the transmission of T. b. gambiense in West and Central Ivory Coast foci: Perspective for a sustainable control of sleeping sickness. Co-pi

  • Paul Sondo -  Biomedical Scientist , PHD

    Paul Sondo - Biomedical Scientist , PHD

    Research and professional experience

    1. Personal Statement

    medical parasitologist by training, i am working as a researcher with permanent position at the ministry of high schools, scientific research and innovation of burkina faso.

    i am interested in malaria and others infectious diseases. over the past five years, my research is mainly focused on assessing antimalarial drug’s efficacy, studying the genetic diversity of plasmodium falciparum and exploring the molecular markers associated with antimalarial drug resistance. i have been awarded the institut merieux young investigator awards 2018.

       

    2. Positions and Employment

    Since 2013: Ministry of High Schools, Scientific Research and Innovation)/ (Government of Burkina Faso): Researcher at IRSS, CNRST

    (2019 – 2022): EDCTP Career Development Fellow) /(EDCTP): Principal Investigator of the SMC-NUT project

    (2017-2018): EDCTP/TDR Clinical Research and Development Fellow/ (WHO-TDR): TDR Fellow at IDDO/WWARN, University of Oxford, United Kingdom

    (2014-2015): WAHRNet Fellow/ (West African Health Research Network): WAHRNet Fellow at KCCR, KNUST, Kumasi, Ghana

       

    3. Selected Peer-reviewed Publications

    Sondo P, Derra K, Rouamba T, Diallo SN, Taconet P, Kazienga A, Ilboudo H, Tahita MC, Valéa I, Sorgho H: Determinants of Plasmodium falciparum multiplicity of infection and genetic diversity in Burkina Faso. Parasites & Vectors 2020, 13:1-12.

    J. Takata, P. Sondo, G S. Humphreys, R. Burrow, B. Maguire, M S. Hossain, D. Das, R J. Commons, R N. Price, P J. Guerin. The WorldWide Antimalarial Resistance Network Clinical Trials Publication Library: A Live, Open-Access Database of Plasmodium Treatment Efficacy Trials. Am. J. Trop. Med. Hyg., 103(1), 2020, pp. 359–368.

    Rouamba T, Sondo P, Derra K, Nakanabo-Diallo S, Bihoun B, Rouamba E, Tarnagda Z, Kazienga A, Valea I, Sorgho H, Pagnoni F, Samadoulougou-Kirakoya F, Tinto H. Optimal Approach and Strategies to Strengthen Pharmacovigilance in Sub-Saharan Africa: A Cohort Study of Patients Treated with First-Line Artemisinin-Based Combination Therapies in the Nanoro Health and Demographic Surveillance System, Burkina Faso. Drug Des Devel Ther. 2020; 14:1507-1521. DOI:10.2147/DDDT.S22485

    P. Sondo, K. Derra, T. Lefevre, S. Diallo Nakanabo, Z. Tarnagda, O. Zampa, A. Kazienga, I. Valea, H. Sorgho, J B. Ouedraogo, T R. Guiguemde, and H. Tinto: Genetically diverse Plasmodium falciparum infections, within-host competition and symptomatic malaria in humans. Scientific Report,2019 Jan 15;9(1):127.DOI:10.1038/s41598-018-36493-y

    WWARN K13 Genotype- Phenotype Study Group: Association of mutations in the Plasmodium falciparum Kelch13 gene (Pf3D7_1343700) with parasite clearance after artemisinin-based treatment - a WWARN individual patient data meta-analysis. BMC Medicine, (2019) 17:1 https://doi.org/10.1186/s12916-018-1207-3

    P. Sondo, K. Derra, S. Diallo‑Nakanabo, Z. Tarnagda, O. Zampa, A. Kazienga, I. Valea, H. Sorgho, E. Owusu‑Dabo, J B. Ouedraogo, T R. Guiguemde, and H. Tinto (2016): Artesunate-Amodiaquine and Artemether-Lumefantrine therapies and selection of Pfcrt and Pfmdr1 alleles in Nanoro, Burkina Faso. Plos One 11(3): e0151565, DOI:10.1371/journal.pone.0151565

    P. Sondo, K. Derra, S. Diallo Nakanabo, Z. Tarnagda I. Valea, H. Sorgho, O. Zampa, A. Kazienga, E. Owusu-Dabo, J B. Ouedraogo, T R. Guiguemdé and H. Tinto: Effectiveness and safety of artesunate-amodiaquine versus artemether-lumefantrine for the unsupervised treatment of uncomplicated malaria in patients of all age groups in Nanoro, Burkina Faso: a randomised open label trial. Malaria Journal 2015, 14:325, DOI 10.1186/s12936-015-0843-8.

    P. Sondo, K. Derra, Z. Tarnagda, S. Diallo Nakanabo, I. Valea, H. Sorgho, O. Zampa, A. Kazienga, J B. Ouedraogo, T R. Guiguemdé and H. Tinto (2015): Dynamic of Pfcrt K76T mutation five years after withdrawal of Chloroquine in Burkina Faso. Pan African Medical Journal vol. 21(101)6437

       

    4. Research Support

    (2019 – 2022: EDCTP Career Development Fellow) /(EDCTP): Principal Investigator of the SMC-NUT project

    (2018) Institut Mérieux Young Investigator Award/ (Institut Mérieux, France)

    (2017-2018): EDCTP/TDR Clinical Research and Development Fellow/ (WHO-TDR): TDR Fellow at IDDO/WWARN, University of Oxford, United Kingdom

    (2014-2015): WAHRNet Fellow/ (West African Health Research Network): WAHRNet Fellow at KCCR, KNUST, Kumasi, Ghana

  • Maminata Traore - Biomedical Scientis, MSc, Phd

    Maminata Traore - Biomedical Scientis, MSc, Phd

    TRAORE/COULIBALY Maminata

    Biomedical scientist, MSc, PhD.

    Studied at University of Ouagadougou, Burkina Faso and Danish Faculty of Pharmaceutical Sciences, University of Copenhagen.

    Research activities focused on infectious diseases - preclinical and clinical evaluation of medicines and phytomedicines - Biochemistry.

    Has successfully achieved around 15 founded projects as investigator and co-investigator.

     

    Academic Position

    - CAMES Director of Research, since 2018

    - Teacher at Catholic University (UCAO) in Bobo-Dioulasso, Burkina Faso and at University Nazi Boni

    - Supervision of PhD, Master, Pharmacy and Medicine theses, around 18.

     

    Administrative position

    -Scientific Director of the Regional Direction of IRSS, based at the Clinical Research Unit of Nanoro, since 2016.

    - Head of the Department “Studies and Monitoring-Evaluation” 2014-2016

    - Head of the Department “Studies and Planning”, 2013-2014

    - Member of AVAREF/OMS technical committee, 2016-2020

    - Member of the national health ethics committee (CERS), 2013-2020

  • Francois Kiemde - Biologist, MSc, PhD

    Francois Kiemde - Biologist, MSc, PhD

    Research and professional experience/ Experience professionnelle (incluant la recherche):

    1. Personal Statement

    (provide a short description of your research interest and/or motivation)

    Biologist by background, he joined the “Institut de Recherche en Sciences de le Santé- Unité de Recherche Clinique de Nanoro” (IRSS-URCN), a public research center based in Nanoro, in July 2009 in the framework of GSK RTS,S phase 3 malaria vaccine trial and other clinical trial. In 2014, he has been engaged by the Ministry of Research of Burkina Faso as Research Assistant and he has been assigned to the “Institut de Recherche en Sciences de le Santé- Unité de Recherche Clinique de Nanoro” (IRSS-URCN).

    In June 2014, he successfully obtained a small grant from the International Society of Infectious Diseases (ISID) to investigate the capacity of natural killer cells to lyse erythrocytes infected by Plasmodium falciparum, and to determine the factors associated with cytotoxicity. The title of the study was “Determination in vitro of cytotoxicity of natural killer cells directed again erythrocytes infected by Plasmodium falciparum during pregnancy. In October 2014, he has been recruited as PhD fellow at KIT-Biomedical Research, Amsterdam, and subsequently by the Academic Medical Centre in Amsterdam (AMC) in May 2015, where he worked on the etiologies of fever episode in children under 5 years of age. He worked under the supervision of Prof Michael Boele van Hensbroek (AMC), Prof Tinto Halidou (IRSS-URCN), Dr Henk Schallig (AMC) and Petra Mens (AMC). During his PhD training, he kept the position of Research Assistant at IRSS-URCN since this PhD was a sandwich PhD program between IRSS-URCN (Burkina Faso) and the Academic Medical Centre in Amsterdam (Amsterdam, The Netherlands). In 2017, his research team won the discovery award from NESTA Foundation to encourage their joint research.

    After obtained his PhD in June 2019, he got back in his home institute where he have been recently appointed as an Associate Researcher by the “Centre National de Recherche Scientifique et Technologique” (CNRST) of which IRSS-URCN is linked.

     

    2. Positions and Employment

     

    Master fellow : December 2008 – July 2009 (University Hopital – Sanou Souro/Bobo – Dioulasso)

    Clinical Field Supervisor : July 2009-December 2014 (CRUN)

    Research Assistant : Decmber 2014-August 2019 (CRUN)

    Research Associate (CNRST) : August 2019 – Ongoing (CRUN)

     

    Other Experience and Professional Memberships

    Other Experience :

    -          Rapid Diagnostic Test development and Evaluation

    -          Developpment of new therapy

    -          Antimicrobial resistance

    3. Selected Peer-reviewed Publications

    1-      RTS,S Clinical Trial Partnership. Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomized, controlled trial. Lancet. 2015;386(9988):31-45. DOI 10.1016/S0140-6736(15)60721-8

    2-      Francois Kiemde, Rene Spijker, Petra F. Mens, Halidou Tinto, Michael Boele and Henk D. F. H. Schallig. Aetiologies of non-malaria febrile episodes in children under 5 years in sub-Saharan Africa. Tropical Medicine and International Health 2016:21 (8):943-955. doi:10.1111/tmi.12722.

    3-      Francois Kiemde, Massa dit Achille Bonko, Marc Christian Tahita, Palpouguini Lompo, Toussaint Rouamba, Halidou Tinto, Michael Boele van Hensbroek, Petra F. Mens and Henk D. F. H. Schallig. Accuracy of a Plasmodium falciparum specific histidine-rich protein 2 rapid diagnostic test in the context of the presence of non-malaria fevers, prior anti-malarial use and seasonal malaria transmission. Malaria Journal 2017: 16: 294. DOI 10.1186/s12936-017-1941-6

    4-      Francois Kiemde, Marc Christian Tahita, Palpouguini Lompo, Toussaint Rouamba, Athanase M. Some, Halidou Tinto, Petra F. Mens, Henk D. F. H. Schallig and Michael Boele van Hensbroek. Treatable causes of fever among children under 5 years in a seasonal malaria transmission area, Nanoro in Burkina Faso. Infectious Diseases of Poverty 2018: 7: 60. DOI 10.1186/s40249-018-0442-3

    5-      Francois Kiemde, Marc Christian Tahita, Massa dit Achille Bonko, Petra F. Mens, Halidou Tinto, Michael Boele van Hensbroek and Henk D. F. H. Schallig. Implementation of a malaria rapid diagnostic test in a rural setting of Nanoro, Burkina Faso: from expectation to reality. Malaria Journal 2018: 17: 316. DOI 10.1186/s12936-018-2468-1

    6-      Francois Kiemde, Massa dit Achille Bonko, Marc Christian Tahita, Palpouguini Lompo, Halidou Tinto, Petra F. Mens, Henk D. F. H. Schallig and Michael Boele van Hensbroek. Can clinical signs or symptoms combined with basic hematology data be used to predict the presence of bacterial infections in febrile children under-5 years? BMC Pediatric 2018: 18:370. DOI 10.1186/s12887-018-1340-3.

    7-      Massa dit Achille Bonko, Francois Kiemde, Marc Christian Tahita, Palpouguini Lompo, Athanase M. Some, Halidou Tinto, Michael Boele van Hensbroek, Petra F. Mens and Henk D. F. H. Schallig. The effect of malaria rapid diagnostic tests results on antimicrobial prescription practices of healthcare workers in Burkina Faso. Annals of Clinical Microbiology and Antimicrobial 2019: 18:5. DOI 10.1186/s12941-019-0304-2.

    8-      Francois Kiemde, Massa dit Achille Bonko, Marc Christian Tahita, Petra F. Mens, Halidou Tinto, Henk D. F. H. Schallig and Michael Boele van Hensbroek. Algorithms for sequential interpretation of a malaria rapid diagnostic test detecting twodifferent targets of Plasmodium species to improve diagnostic accuracy in a rural setting (Nanoro, Burkina Faso). PLoS ONE 2019: 14(2): e0211801. DOI 10.1371/journal.pone.0211801.

    4. Research Support

    1. International Society of Infectious diseases; 2014; Title: NK Celle and Pregnancy: Determination in vitro of cytotoxicity of Natural Killer cells directed against erythrocytes infected by Plasmodium falciparum during pregnancy.

    Start date: June 2018; End date: August 2019

     

    2. Discovery Award from NESTA Foundation; 2017: RAPDIF: a rapid diagnostic test for undifferentiated fevers. Amsterdam, The Netherlands.

    Start date: September 2017; End date: May 2018

    3. EDCTP Career Development; 2019; Title: e-MANIC: Development and evaluation of an electronic algorithm using a combination of a two-step malaria rapid diagnostic test detecting PfHRP2 and pLDH, and other rapid diagnostic tools for the management of febrile illness in children under 5 years attending outpatient facilities in Burkina Faso.

    Start date: December 2020; End date: November 2023

  • Ousmane Troare - Biologist, MSc, PhD

    Ousmane Troare - Biologist, MSc, PhD

    Biography

    Ousmane TRAORE earned his MSc and PhD in applied biology at Nazi Boni University, Bobo-Dioulasso (Burkina Faso). From 2008 to date, his research focuses on immunology and parasitology. During his MSc training, he developed an operational procedure for antisera production locally for serological diagnosis of parasitosis. At PhD level, he made agroundbreaking work on the immunological basis of placental malaria and described a possibility to develop an alternative diagnostic tool to detect malaria early in pregnancy. He has a decade of experience in clinical research (drugs and vaccines) on malaria. As research assistant at the Clinical Research Unit of Nanoro - Research Institute of Health Sciences, Ousmane TRAORE is currently serving as lab manager on a Phase II malaria vaccine trial (since January 2019). In parallel he undertook to find funding for his own researches.

    Email: ousmane.traore@crun.bf

     

    Personal Statement

    I am highly interested in infectious diseases, particularly malaria research applied to maternal and infant health, specifically understanding the relationship between immune responses and recommended interventions against malaria. In addition, I foresee to undertake some preclinical immunological researches, in order to promote traditional therapeutic recipes.

    Selected Peer-reviewed Publications (See in Publication Section)

  • Salou Diallo - Biologist, MSc, PhD

    Salou Diallo - Biologist, MSc, PhD

    Biographical Sketch

    Diallo Salou is a Biologist by background. At the “Université de Ouagadougou” he obtained his Master I in Biochemistry/Microbiology in 2005. He will join the “Université Nazi Boni/Bobo Dioulasso” in 2009, where he undertook his Master 2 graduation in Applied Biology and Biologic systems modelization. Since 2012 Diallo Salou is involved in PhD training.

    His research activity focused on Biochemistry/Hematology, particularly towards the research of iron metabolism, relationship between malaria and iron status in childbearing women. He worked since 2014 up to date as research associate at “Institut de Recherche en Sciences de la Santé” (IRSS), Burkina Faso.

    He worked previously at “Centre de Recherche en Santé de Nouna” in 2006 where he participated to investigation on drugs quality. In 2007, Diallo Salou joined the Clinical Research Unit of Nanoro, where he occupied successively:

    1.    April-December 2007: Lab Supervisor

    2.    April 2009-December 2010: Field Supervisor on RTS,S vaccine trial

    3.    March 2011-December 2013: Study Site Coordinator on EPI-Mal study

    4.    April 2011-February 2014: Lab Supervisor on Palufer Study

    5.    January 2016-December 2016: Study Site Coordinator on Palubac study

    6.    March 2017-October 2017: Study Site Coordinator on Novac study

    From 2012 to 2016, Diallo Salou undertook several national/international trainings to strengthen his research capacities:

    1.    19-30 March 2012: NIH; NIAID and MRTC_Bamako/Mali; Inaugural West African regional Workshop on Protozoan Pathogens

    2.    September-October 2012 : Institut de Recherche des Sciences de la Santé (IRSS)/Ouagadougou ; Data analysis

    3.    7-26 January 2013: ATCT/IPT/JICA. Tunis/Tunisia    Molecular biochemistry in Health Application

    4.    September-October 2013: CIBEMAG Institute /Ghana; English Course

    5.    September-October 2014: MRC International Nutrition Group Keneba/The GAMBIA; “Hepcidin and Global Health”; Acuri automate project

    6.    17 October - 25 November 2016: University of Antwerp (Belgium) International course in Epidemiology, Biostatistics & Qualitative research methods (EBQ)

    Selected Peer-reviewed Publications (See in Publication Section)</strong

    1.    Loretta Brabin, Stephen A. Roberts, Sabine Gies, Andrew Nelson, Salou Diallo, Christopher J. Stewart, Adama Kazienga, Julia Birtles, Sayouba Ouedraogo, Yves Claeys, Halidou Tinto10, Umberto d’Alessandro E. Brian Faragher and Bernard Brabin. Effects of long-term weekly iron and folic acid supplementation on lower genital tract infection – a double blind, randomised controlled trial in Burkina Faso. BMC medicine 27 Nov 2017. DOI 10.1186/s12916-017-0967-5

    2.    The RTS,S Clinical Trials Partnership: Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase Randomized, Controlled Trial in Children and Young Infants at 11 African Sites. PLoS Med 2014, 11(7): e1001685. doi:10.1371/journal.pmed.1001685

    3.    Halidou Tinto, Salou Diallo, Issaka Zongo, Issa Guiraud, Innocent Valea, Adama Kazienga, Herve Kpoda , Hermann Sorgho, Jean-Bosco Ouedraogo, Tinga Robert Guiguemde,Umberto D’Alessandro: Effectiveness of artesunate–amodiaquinevs. artemether–lumefantrine for the treatment of uncomplicated falciparum malaria in Nanoro, Burkina Faso: a non-inferiority randomized trial. Tropical Medicine and International Health 2014, doi:10.1111/tmi.12274

    4.    Maike Tipke, Salou Diallo, Boubacar Coulibaly, Dominic Störzinger, Torsten Hoppe-Tichy, Ali Sie and Olaf Müller: Substandard anti-malarial drugs in Burkina Faso. Malaria Journal 2008, 7:95 doi:10.1186/1475-2875-7-95

  • Adelaide Compaore - MSC, Sociologist

    Adelaide Compaore - MSC, Sociologist

    Research and professional experience/ Experience professionnelle (incluant la recherche):

    Personal Statement

    Adélaïde Compaoré is the head of the socio-anthropology research team. She joined the Clinical Research Unit of Nanoro (CRUN), Burkina Faso as a research fellow in social science in 2010. Since then she has been actively involved in the implementation of research projects. Her first experience with the research started in a clinical trial funded by the NIH, assessing the risk of malaria prior to and during early pregnancy in nulliparous women receiving long-term weekly iron and folic acid supplementation. In this trial, her responsibilities were to conduct qualitative research on the acceptability of weekly iron supplementation. This allows her to produce under the supervision of Docteur Loretta Brabin, two papers: the first on the perception of iron supplementation published in maternal and child Health journal and the second on adolescent women adherence to weekly supplementation in the Reproductive Health Journal. Her second experience was in a community-based study, which is a FP7-funded multi-centric study. This study aimed at assessing the impact of Community Screening Scheduled Test in addition to the standard IPTp-SP as an alternative to IPTp-SP alone in the prevention of malaria in pregnancy. She was in charge of conducting field work of the anthropology work package in Burkina Faso and Benin. She published a paper in Malaria Journal in 2018 under the supervision of Koen Peeters, the head of the Medical Anthropology Unit, at the Institute of Tropical Medicine (ITM) in Antwerp.

    All these experiences have contributed to nurture her interest for the research. Therefore, she has started her carrier development by undertaking a PhD programme. Her research topic entitled “Understanding antimicrobials use: A mixed methods research of rural communities in Burkina Faso”, seeks to understand the cultural and socioeconomic conditions that drive antibiotic use in rural Burkina Faso. The research is being supervised collaboratively by the CRUN, the ITM, and the AMRIWA Consortium (University of Helsinki).

    adelhaid.compaore@gmail.com.

    Research experience

    Study title Period Sponsor
    1 Leveraging improved nutrition preconception, during pregnancy and postpartum in Sub-Saharan Africa through novel intervention models, at the University of Southampton` 2018-2021 The National Institute for Health Research (NIHR)
    2 Impact of improved diagnostic tools, practices and Training and Communication on acute fever case management and antibiotic prescriptions for children and adolescents presenting at outpatient facilities in Burkina Faso 2019-2021 FIND
    3 A hospital antibiotic stewardship program in Burkina Faso: studying implementation, effectiveness, and costs 2016 - Ongoing Institute of Tropical Medicine
    4 Phase IV study to assess the clinical safety and effectiveness after the introduction of a fixed dose of Artemisinin Pyramax® (Pyronaridine-Artesunate) combination therapy in the health district of Nanoro, Burkina Faso 2017 - Ongoing INDEPTH Network
    5 Community-based scheduled screening and treatment of malaria in pregnancy for improved maternal and infant health: a cluster-randomized trial (COSMIC)'' 2015 - 2016 Academic Medical Centre (AMC), Netherlands
    6 Malaria risk prior to and during early pregnancy in nulliparous women receiving long term weekly iron and folic acid supplementation (WIFS): A non-inferiority randomized controlled trial (WCT01210040) 2011 - 2014 Liverpool School of Tropical Medicine

    Publications

     

    1.       Compaore A, Gies S, Brabin B, Tinto H, Brabin L. (2014). ‘‘There is iron and iron…’’ Burkinabe` women’s perceptions of iron supplementation: a qualitative study. Maternal and Child Health Journal. 2014 Oct;18(8):1976-84. doi: 10.1007/s10995-014-1443-x

    2.       Compaoré A, Gies S, Brabin B, Tinto H, Brabin L. (2018). Community approval required for periconceptional adolescent adherence to weekly iron and/or folic acid supplementation: a qualitative study in rural Burkina Faso. Reproductive Health. 2018 Mar 14;15(1):15:48.  doi: 10.1186/s12978-018-0490-y

    3.       Compaoré A, Dierickx S, Jaiteh F, Nahum A, Bohissou TFE, Tinto H, Scott S, D'Alessandro U, Schallig H, Grietens KP. (2018). Fear and rumours regarding placental biopsies in a malaria-in-pregnancy trial in Benin. Malaria Journal. 2018 Nov 15;17(1):425.  doi: 10.1186/s12936-018-2578-9

    4.       Rouamba T, Sondo P, Yerbanga IW, Compaore A, Akweongo P, Baiden R, et al. High adherence level to artemisinin-based combination therapies in rural settlement 11 years after their introduction in the health system, Nanoro,Burkina Faso. Patient Prefer Adherence. 2019;13:371–80. doi  10.2147/PPA.S190927

    5.       Watson D, Kehoe SH, Erzse A, Compaoré A, Debpuur C, Nonterah EA, Sorgho H, Norris SA, Hofman KJ, Lawrence W, Newell ML, Godfrey KM, Ward KA, Barker M; INPreP group. Community perspectives on maternal and child health during nutrition and economic transition in sub-Saharan Africa. Public Health Nutr. 2020 Sep 15:1-9. doi: 10.1017/S1368980020003018.

    6.       Compaoré, A., Ouedraogo, K., Boua, P. R., Watson, D., Kehoe, S. H., Newell, M. L., Tinto, H., Barker, M., Sorgho, H., & INPreP group (2020). 'Men are not playing their roles', maternal and child nutrition in Nanoro, Burkina Faso. Public health nutrition, 1–11. Advance online publication. doi.org/10.1017/S1368980020003365

  • Karim Derra - MSc, Phd Candidate

    Karim Derra - MSc, Phd Candidate

    Demographer with a Mathematician background. Since 2009, I am the Nanoro HDSS Manager at the Clinical Research Unit of Nanoro (CRUN), IRSS-DRCO, Burkina Faso. I am also a PhD candidate in Demography at Centre for Demographic Research (UCL Belgium) with a PhD project aiming to address a critical issue in malaria control, i.e. developing news tools to accurately assess malaria attributable mortality. My research activities are focused on population and health, particularly on malaria.

     

    I have been involved in Epidemiology and Public Health studies as well. I have a good experience on electronic data collection and analysis of longitudinal data.

    I graduated from IFORD (Institut de Formation et de Recherche Démographiques) in Cameroon in 2008 with MSc. in Demography. I worked from 2008 to 2009 as research officer for the department of population and development at SP/CONAPO, Burkina Faso. In 2009, I joined CRUN to help establish the Nanoro HDSS. My main papers have been published in International Journal of Epidemiology, Global Health Action, Malaria Journal and Plos One.

     

    Karim Derra, MSc. Demography, PhD candidate

    Organisation: CRUN/Nanoro HDSS, Burkina Faso

    Position: Nanoro HDSS Manager

    Contact: kderra@crun.bf