 | Massa Dit Achille Bonko, Francois Kiemde, Marc Christian Tahita, Palpouguini Lompo, Athanase M Some, Halidou Tinto, Michael Boele Hensbroek, Petra F Mens, Henk D F H Schallig The effect of malaria rapid diagnostic tests results on antimicrobial prescription practices of health care workers in Burkina Faso (Journal Article) In: Ann. Clin. Microbiol. Antimicrob., vol. 18, no. 1, pp. 5, 2019, ISSN: 1476-0711. @article{Bonko2019-kx,
title = {The effect of malaria rapid diagnostic tests results on antimicrobial prescription practices of health care workers in Burkina Faso},
author = {Massa Dit Achille Bonko and Francois Kiemde and Marc Christian Tahita and Palpouguini Lompo and Athanase M Some and Halidou Tinto and Michael Boele Hensbroek and Petra F Mens and Henk D F H Schallig},
doi = {10.1186/s12941-019-0304-2},
issn = {1476-0711},
year = {2019},
date = {2019-01-01},
urldate = {2019-01-01},
journal = {Ann. Clin. Microbiol. Antimicrob.},
volume = {18},
number = {1},
pages = {5},
publisher = {Springer Science and Business Media LLC},
abstract = {BACKGROUND: Malaria rapid diagnostic tests (RDT) are widely used
in endemic areas in order to comply with the recommendation that
malaria treatment should only be given after the clinical
diagnosis has been confirmed by RDT or microscopy. However, the
overestimation of malaria infection with the use of PfHRP2 based
RDT, makes the management of febrile illnesses more challenging.
This study aimed to assess the effect of the use of malaria RDT
on antimicrobial prescription practices. METHODS: A prospective
study was conducted among febrile children under-5 years of age
attending four health facilities and the referral hospital in
the Nanoro Health District (Burkina Faso). To assess the effect
of malaria RDT testing on the prescriptions of antimicrobials in
febrile children, the initial diagnosis and antimicrobial
prescriptions following a malaria RDT testing were recorded. The
necessity of these prescriptions was subsequently checked by
assessing the actual cause of fever by expert malaria microscopy
and a microbiology analysis of blood, urine, stool and
nasopharynx swabs that were collected from febrile cases to
determine the actual cause of the fever episode. RESULTS:
Malaria was diagnosed by nurses, who are the primary health care
providers, with a malaria RDT in 72.7% (798/1098) of febrile
children, but only 53.7% (589/1097) cases could be confirmed by
expert microscopy. Health care workers were likely to prescribe
antimalarials to malaria positive RDT compared to malaria negative RDT (RR = 7.7},
keywords = {Antibiotic; Antimicrobial; Bacteria and parasites; Fever; Malaria; Prescription},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Malaria rapid diagnostic tests (RDT) are widely used
in endemic areas in order to comply with the recommendation that
malaria treatment should only be given after the clinical
diagnosis has been confirmed by RDT or microscopy. However, the
overestimation of malaria infection with the use of PfHRP2 based
RDT, makes the management of febrile illnesses more challenging.
This study aimed to assess the effect of the use of malaria RDT
on antimicrobial prescription practices. METHODS: A prospective
study was conducted among febrile children under-5 years of age
attending four health facilities and the referral hospital in
the Nanoro Health District (Burkina Faso). To assess the effect
of malaria RDT testing on the prescriptions of antimicrobials in
febrile children, the initial diagnosis and antimicrobial
prescriptions following a malaria RDT testing were recorded. The
necessity of these prescriptions was subsequently checked by
assessing the actual cause of fever by expert malaria microscopy
and a microbiology analysis of blood, urine, stool and
nasopharynx swabs that were collected from febrile cases to
determine the actual cause of the fever episode. RESULTS:
Malaria was diagnosed by nurses, who are the primary health care
providers, with a malaria RDT in 72.7% (798/1098) of febrile
children, but only 53.7% (589/1097) cases could be confirmed by
expert microscopy. Health care workers were likely to prescribe
antimalarials to malaria positive RDT compared to malaria negative RDT (RR = 7.7 |
