Publications

@article{Bonko2021-kv,

title = {Antibiotic susceptibility of Staphylococcus aureus and  Streptococcus pneumoniae isolates from the nasopharynx of febrile  children under 5 years in Nanoro, Burkina Faso},

author = {Massa Dit Achille Bonko and Palpouguini Lompo and Marc Christian Tahita and Francois Kiemde and Ibrahima Karama and Athanase M Som\'{e} and Petra F Mens and Sandra Menting and Halidou Tinto and Henk D F H Schallig},

doi = {10.3390/antibiotics10040444},

issn = {2079-6382},

year  = {2021},

date = {2021-04-15},

urldate = {2021-04-15},

journal = {Antibiotics (Basel)},

volume = {10},

number = {4},

abstract = {(1) Background: nasopharynx colonization by resistant 

 Staphylococcus aureus and Streptococcus pneumoniae can lead to 

 serious diseases. Emerging resistance to antibiotics commonly 

 used to treat infections due to these pathogens poses a serious 

 threat to the health system. The present study aimed to determine 

 the antibiotic susceptibility of S. aureus and S. pneumoniae 

 isolates from the febrile children's nasopharynx under 5 years in 

 Nanoro (Burkina Faso). (2) Methods: bacterial isolates were 

 identified from nasopharyngeal swabs prospectively collected from 

 629 febrile children. Antibiotic susceptibility of S. aureus and 

 S. pneumoniae isolates was assessed by Kirby-Bauer method and 

 results were interpreted according to the Clinical and Laboratory 

 Standard Institute guidelines. (3) Results: bacterial 

 colonization was confirmed in 154 (24.5%) of children of whom 

 96.1% carried S. aureus, 3.2% had S. pneumoniae, and 0.6% 

 carried both bacteria. S. aureus isolates showed alarming 

 resistance to penicillin (96.0%) and S. pneumoniae was highly 

 resistant to tetracycline (100%) and 

 trimethoprim-sulfamethoxazole (83.3%), and moderately resistant 

 to penicillin (50.0%). Furthermore, 4.0% of S. aureus 

 identified were methicillin resistant. (4) Conclusion: this study 

 showed concerning resistance rates to antibiotics to treat 

 suspected bacterial respiratory tract infections. The work 

 highlights the necessity to implement continuous antibiotic 

 resistance surveillance.},

note = {PMID: 33920987 

PMCID: PMC8071235},

keywords = {antibiotics, children; nasopharynx, resistance, Staphylococcus aureus, Streptococcus pneumoniae},

pubstate = {published},

tppubtype = {article}

}