| Massa Dit Achille Bonko, Palpouguini Lompo, Marc Christian Tahita, Francois Kiemde, Ibrahima Karama, Athanase M Somé, Petra F Mens, Sandra Menting, Halidou Tinto, Henk D F H Schallig Antibiotic susceptibility of Staphylococcus aureus and Streptococcus pneumoniae isolates from the nasopharynx of febrile children under 5 years in Nanoro, Burkina Faso (Journal Article) In: Antibiotics (Basel), vol. 10, no. 4, 2021, ISSN: 2079-6382, (PMID: 33920987
PMCID: PMC8071235). @article{Bonko2021-kv,
title = {Antibiotic susceptibility of Staphylococcus aureus and Streptococcus pneumoniae isolates from the nasopharynx of febrile children under 5 years in Nanoro, Burkina Faso},
author = {Massa Dit Achille Bonko and Palpouguini Lompo and Marc Christian Tahita and Francois Kiemde and Ibrahima Karama and Athanase M Som\'{e} and Petra F Mens and Sandra Menting and Halidou Tinto and Henk D F H Schallig},
doi = {10.3390/antibiotics10040444},
issn = {2079-6382},
year = {2021},
date = {2021-04-15},
urldate = {2021-04-15},
journal = {Antibiotics (Basel)},
volume = {10},
number = {4},
abstract = {(1) Background: nasopharynx colonization by resistant
Staphylococcus aureus and Streptococcus pneumoniae can lead to
serious diseases. Emerging resistance to antibiotics commonly
used to treat infections due to these pathogens poses a serious
threat to the health system. The present study aimed to determine
the antibiotic susceptibility of S. aureus and S. pneumoniae
isolates from the febrile children's nasopharynx under 5 years in
Nanoro (Burkina Faso). (2) Methods: bacterial isolates were
identified from nasopharyngeal swabs prospectively collected from
629 febrile children. Antibiotic susceptibility of S. aureus and
S. pneumoniae isolates was assessed by Kirby-Bauer method and
results were interpreted according to the Clinical and Laboratory
Standard Institute guidelines. (3) Results: bacterial
colonization was confirmed in 154 (24.5%) of children of whom
96.1% carried S. aureus, 3.2% had S. pneumoniae, and 0.6%
carried both bacteria. S. aureus isolates showed alarming
resistance to penicillin (96.0%) and S. pneumoniae was highly
resistant to tetracycline (100%) and
trimethoprim-sulfamethoxazole (83.3%), and moderately resistant
to penicillin (50.0%). Furthermore, 4.0% of S. aureus
identified were methicillin resistant. (4) Conclusion: this study
showed concerning resistance rates to antibiotics to treat
suspected bacterial respiratory tract infections. The work
highlights the necessity to implement continuous antibiotic
resistance surveillance.},
note = {PMID: 33920987
PMCID: PMC8071235},
keywords = {antibiotics, children; nasopharynx, resistance, Staphylococcus aureus, Streptococcus pneumoniae},
pubstate = {published},
tppubtype = {article}
}
(1) Background: nasopharynx colonization by resistant
Staphylococcus aureus and Streptococcus pneumoniae can lead to
serious diseases. Emerging resistance to antibiotics commonly
used to treat infections due to these pathogens poses a serious
threat to the health system. The present study aimed to determine
the antibiotic susceptibility of S. aureus and S. pneumoniae
isolates from the febrile children’s nasopharynx under 5 years in
Nanoro (Burkina Faso). (2) Methods: bacterial isolates were
identified from nasopharyngeal swabs prospectively collected from
629 febrile children. Antibiotic susceptibility of S. aureus and
S. pneumoniae isolates was assessed by Kirby-Bauer method and
results were interpreted according to the Clinical and Laboratory
Standard Institute guidelines. (3) Results: bacterial
colonization was confirmed in 154 (24.5%) of children of whom
96.1% carried S. aureus, 3.2% had S. pneumoniae, and 0.6%
carried both bacteria. S. aureus isolates showed alarming
resistance to penicillin (96.0%) and S. pneumoniae was highly
resistant to tetracycline (100%) and
trimethoprim-sulfamethoxazole (83.3%), and moderately resistant
to penicillin (50.0%). Furthermore, 4.0% of S. aureus
identified were methicillin resistant. (4) Conclusion: this study
showed concerning resistance rates to antibiotics to treat
suspected bacterial respiratory tract infections. The work
highlights the necessity to implement continuous antibiotic
resistance surveillance. |