@article{Jaspard2021-bl,

title = {Clinical presentation, outcomes and factors associated with  mortality: A prospective study from three COVID-19 referral  care centres in West Africa},

author = {Marie Jaspard and Mamadou Saliou Sow and Sylvain Juchet and Eric Diender\'{e} and Beatrice Serra and Richard Kojan and Billy Sivahera and Caroline Martin and Moumouni Kinda and Hans-Joerg Lang and Fod\'{e} Bangaly Sako and Fod\'{e} Amara Traor\'{e} and Eudoxie Koumbem and Halidou Tinto and Adama Sanou and Apoline Sondo and Flavien Kabor\'{e} and Joseph Donamou and Jean-Paul-Yassa Guilavogui and Fanny Velardo and Brice Bicaba and Olivier Marcy and Augustin Augier and Sani Sayadi and Armel Poda and Sakoba Keita and Xavier Anglaret and Denis Malvy and COVISTA group},

doi = {10.1016/j.ijid.2021.05.024},

issn = {1878-3511 1201-9712},

year  = {2021},

date = {2021-07-01},

urldate = {2021-07-01},

journal = {Int. J. Infect. Dis.},

volume = {108},

pages = {45--52},

publisher = {Elsevier BV},

abstract = {OBJECTIVES: The overall death toll from COVID-19 in Africa is 

 reported to be low but there is little individual-level evidence 

 on the severity of the disease. This study examined the clinical 

 spectrum and outcome of patients monitored in COVID-19 care 

 centres (CCCs) in two West-African countries. METHODS: Burkina 

 Faso and Guinea set up referral CCCs to hospitalise all 

 symptomatic SARS-CoV-2 carriers, regardless of the severity of 

 their symptoms. Data collected from hospitalised patients by 

 November 2020 are presented. RESULT: A total of 1,805 patients 

 (64% men, median age 41 years) were admitted with COVID-19. 

 Symptoms lasted for a median of 7 days (IQR 4-11). During 

 hospitalisation, 443 (25%) had a SpO2 \< 94% at least once, 237 

 (13%) received oxygen and 266 (15%) took corticosteroids. 

 Mortality was 5% overall, and 1%, 5% and 14% in patients 

 aged \<40, 40-59 and $geq$60 years, respectively. In 

 multivariable analysis, the risk of death was higher in men (aOR 

 2.0, 95% CI 1.1; 3.6), people aged $geq$60 years (aOR 2.9, 

 95% CI 1.7; 4.8) and those with chronic hypertension (aOR 2.1, 

 95% CI 1.2; 3.4). CONCLUSION: COVID-19 is as severe in Africa 

 as elsewhere, and there must be more vigilance for common risk 

 factors such as older age and hypertension.},

note = {Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

PMID: 34000419 

PMCID: PMC8120805},

keywords = {Adult, Aged, Burkina Faso/epidemiology, Comorbidities, COVID-19, Female, Hospitalization, Humans, Male, Mortality, Prospective Studies, Referral and Consultation, SARS-Cov-2, sub-Saharan Africa},

pubstate = {published},

tppubtype = {article}

}